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RISS 인기검색어
- 검색키워드
- 저자 : ( Yukitoshi Toyoda ) (검색결과 4 건)
- 무료
- 기관 내 무료
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( Kazuhiko Natori ),( Susumu Ishihara ),( Daisuke Nagase ),( Yukitoshi Toyoda ),( Akiko Sakai ),( Motohiro Kato ),( Yasunobu Kuraishi ),( Kazuho Arai ),( Haruka Izumi ) 대한내과학회 2014 대한내과학회 추계학술발표논문집 Vol.2014 No.1
Background: Chemotherapy of the elderly person was common practice. Clinical outcome is force to equal an adult. However, a patient 90 years or older has a high risk of chemotherapy. We report our experience with two patients of malignant lymphoma 90 years or older. Methods: In periods from 2003 to 2013, patients whom malignant lymphoma was diagnosed in our hospital, we extracted a case 90 years or older. We reviewed gender, clinical stage, chemotherapy, dosage, clinical outcome, and prognosis. Results: Case 1: 91-year-old male, fi rst manifestation was systemic lymphadenopathy, Sufferings from dyspnea, he became the hospitalization. Pleural effusion was revealed, after lymph node biopsy, he was diagnosed non-Hodgkin`s lymphoma diffuse large B cell (NHL DLBCL). We performed chemotherapy by his strong wish. After 3 course of R-CHOP (dosage 50%), he achieved partial remission and was able to return to the house. He died after a diagnosis in 13 months. Case 2: 90-year-old female, fi rst manifestation was dysfunction of artifi cial denture, she had a checkup in dentistry. At the time dentist discovered a mass lesion and performed biopsy. Diagnosis was NHL DLBCL, and she was referred and had performed chemotherapy our hospital. After 6 course of R-CHOP (dosage 65%), she achieved complete remission and he still alive. Conclusions: It is got enough cinical outcome from even a case 90 years or older bychemotherapy. However, drug reduction criteria are not established that are indispensable for safe chemot
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( Kazuhiko Natori ),( Daisuke Nagase ),( Susumu Ishihara ),( Yukitoshi Toyoda ),( Akiko Sakai ),( Motohiro Kato ),( Yasunobu Kuraishi ),( Kazuho Arai ),( Haruka Izumi ) 대한내과학회 2014 대한내과학회 추계학술발표논문집 Vol.2014 No.1
Background: Though oral infection represented by caries and periodontal disease is the infectious disease that is thought with life-style related diseases generally. Including hematological malignancy, the infectious disease research before taking anticancer drug treatment is important. A potential infectious disease may bring about a fatal infectious disease for bone marrow suppression period. We report it this time about an oral surgery area as a search before treatment of the malignant lymphoma. Methods: In eight years from 2003 to 2012, we intended for a case in newly diagosed malignant lymphoma in our hospital. We reviewed having consultation or not of the oral surgery, treatment contents, having exodontia or not. Results: Among 383 patients, the oral surgery consultation was 271 cases, male female ration was 150/121. T, and the age median was 67years. It was 154 cases that it was judged that treatment was necessary. The case performed exodontia was 53 cases. Among 53 patients, 33 cases were progression stages. Conclusions: With the onset of febril neutropenia, the infectious disease that is not seen occurs with the normal immune status. An oral cavity lesion is a neighborhood of the central nerve system and is in very danger. Fortunately, there was not the case of death for the infection of the oral cavity lesion. However, malignant neoplasms patients has much dentistry treatment, and the exodontia number accounts for the majority, too.
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Poster Session : PS 0332 ; Hematology : Malignant Lymphoma That Diagnosed from Gastric Biopsy
( Kazuhiko Natori ),( Daisuke Nagase ),( Susumu Ishihara ),( Yukitoshi Toyoda ),( Sakai ),( Motohiro Kato ),( Yasunobu Kuraishi ),( Kazuho Arai ),( Haruka Izumi ) 대한내과학회 2014 대한내과학회 추계학술발표논문집 Vol.2014 No.1
Background: Primary malignant gastrointestinal lymphoma accounts for 1-4% of malignant gastrointestinal tumors. Herein, we report the results of our study on 32 patients diagnosed from biopsy of stomach. Methods: From 2003 to 2012, we intended for 466 patients whom malignant lymphoma. 32 patients were selected. All patients were followed up until death or untile December 2013. Survival was measured from the diagnosis of multiple cancer to time of death or last contact. Results: All cases are 32 cases, gender male 16 cases, female 16 cases. Median age is 68 years, performance status is grade 0 20 cases, grade 1 7 cases, 2 grade 1 case, 3 grade 1 case, grade4 3 cases. Pathological fi ndings, 31 cases are non-Hodgkin`s lymphoma, 1 case is adult T cell lymphoma. Immnochemical stain fi ndings, diffuse laerge B cell type 21 cases, MALT lymphoma 8 cases, T cell lymphoma 1 cases, unknown 1 case. Clinical stage by Ann aobor classifi cation, stage IV is 13 cases, and Lugno classifi cation, L-I 17 cases, L-II-1 1 case, L-II-2 1 case. About therapy, CHOP or CHO therapy 3 cases(because of HBV active infection), rituximab +CHOP therapy 15 cases, Radiation therapy 4 cases, CHOP therapy after radiation therapy 2 cases, CHOP therapy after total gastrectomy 2 cases Eradication alone 1 case, chemotherapy ( CHOP therapy ) after eradication 1 case. Median survival time is not reached, 5 years survival rate is 66. 7%. At last December 2013, surviver is 23 cases, dead is 9 cases. Conclusions: The benefits of surgical treatment include decreased tumor amount by resection of local and regional lymph nodes, and more accurate diagnosis of the disease stage. However, we consider that the disadvantages of the majority of the recent therapies can be avoided by performing endoscopic examination and improving diagnostic imaging.
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( Kazuhiko Natori ),( Susumu Ishihara ),( Daisuke Nagase ),( Yukitoshi Toyoda ),( Akiko Shibuya ),( Motohiro Kato ),( Yasunobu Kuraishi ),( Kazuho Arai ),( Haruka Izumi ) 대한내과학회 2014 대한내과학회 추계학술발표논문집 Vol.2014 No.1
Background: Colon cancer accounts for number of cases, a superior of the cause of death like gastric cancer, lung cancer. Wereport aggregates the multiple neoplasms including hematological malignancy and colon cancer. Methods: In the case that hematologic malignancy was diagnosed in our hospital by 1988 from 2013, The multiple cancer including colon cancer and the hematologic malignancy was 45 cases. So we reviewed and reported. Results: All cases are 45 cases, including female 14 cases, male 31cases, synchronous type 15 cases, metechronous type 30 cases. Multiple neoplasms consist of double cancer 33 cases, triple cancer 11 cases, quadrop cancer 1case. The median interval period in double cancer is 58 months. Hematological malignancy consist of non-Hodgkin`s lymphoma 24 cases, Hodgkin`s lymphoma 1 case, myelodysplastic syndrome 6 cases, chronic myelogeneou leukemia 3 cases, multiple myeloma 5 cases, macroglobrinemia 2 cases, acute lymphoblastic leukemia 3 cases, acute myelogeneous leukemia 2 case. Chronic lymphocytic leukemia 1 case. The sites of colon cancer studied 41 cases and results were that ascending colon 7cases, transverous colon 3cases, descending colon 2cases, sigmoid colon 9cases, rectum 8 cases. In a double cancer, 12 cases were preceding colon cancer and 9 cases were preceding hematological malignancy, an interval of the colon cancer precedence cases, the median time was 83M, hematological malignancy precedence cases was 42M. Median survival time is 15M, about cause of death, 21 cases still alive and 24 cases are dead. In 24 cases, hematological malignancy 17 cases, colon cancer 7 cases. Conclusions: In the case of hematological malignancy precedence case, 4 of 9 colon cancer occurred within three years. We should take attention about incidence of other malignancies, particularly those that occur from gastrointestinal tract and serious observation about distant metastasis site, such as liver and lung.
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