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      • Pregnancy and neonatal outcomes in Group B Streptococcus agalactiae (GBS) infection during pregnancy

        ( Yaeheun Lee ),( Chanmi Lim ),( Sunyoung Jung ),( Juyoung Kim ),( Sukyoung Kim ) 대한산부인과학회 2016 대한산부인과학회 학술대회 Vol.102 No.-

        목적: The aim of this study was to examine whether GBS was associated with subsequent preterm delivery and neonatal outcome 방법: This study design is retrospective cross-sectional study. Maternal and neonatal outcomes were examined among singleton pregnant woman with preterm delivery(from 24+0 weeks to 36+6 weeks) who underwent GBS-analysis(n=230) during this pregnancy. Data were reviewed between January 2015 to June 2016 in Gil hospital. We compared with clinical characteristics, obstetrical and perinatal complications between GBS infected and non-infected pregnant women and we evaluated efficacy of screening test in GBS culture 결과: There were 230 singleton pregnant women under study, of whom 15 pregnant woman were confirmed GBS infection during this pregnancy. Parity, maternal STD infection, chorioamnionitis, type of delivery, cause of preterm delivery, neonatal history of respiratory distress syndrome remained independently associated with GBS infection in pregnacy. There was lower Apgar score (1min) in babies who GBS-infected mothers delivered than in the uninfected (6.5±2.6, p=0.045). The gestational age, maternal age, neonatal birth weight, neonatal hospitalization period, days of ventilator care, neonatal CRP(within 3days) and Apgar score 5 (min) were not significantly associated 결론: Maternal GBS infection is associated with adverse neonatal outcome Apgar score (1min). Futher studies, with more sensitive and rapid diagnosis technique and close follw-up of neonates of GBS-infected mothers are needed.

      • Correlation of preoperative biomarkers with severity of adhesion in endometriosis

        ( Yoojung Lee ),( Yaeheun Lee ),( Seungho Lee ),( Sunyong Jung ),( Seungjoo Chon ),( Daun Jung ) 대한산부인과학회 2018 대한산부인과학회 학술대회 Vol.104 No.-

        Objective: This study was undertaken to evaluate the preoperative correlation of serum markers and pelvic adhesions in endometriosis patients, and to explore their clinical value for prediction. Methods: A total of 152 women who underwent surgery for endometriosis were reviewed retrospectively. Preoperative basic serum laboratory test and CA 125 were analyzed, and the adhesion score calculated. The group with less than 28 points was defined as a mild adhesion group, and a score of 28 or more as a severe adhesion group. Results: CA 125 was significantly higher in severe adhesion group than mild adhesion group (P = 0.003). The statistically significant risk factors for adhesion were CA 125 35 U/mL (OR [odds ratio], 5.362; 95% CI [confidence interval], 2.519 - 11.415; P < 0.001), size of largest cyst 5 cm (OR, 2.626; 95% CI, 1.104 - 6.241; P = 0.029), and WBC 5,680 /L (OR, 2.279; 95% CI, 1.025 - 5.065; P = 0.043). The adhesion score was significantly higher in the CA 125 35 U/mL group than the CA 125 < 35 U/mL group (P < 0.001). Conclusion: CA 125, size of largest cyst and WBC are associated with pelvic adhesions. In particular, CA 125 was the most significant factor. Patients with preoperative CA 125 higher than 35 U/mL are at high risk for pelvic adhesion.

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