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RISS 인기검색어
- 검색키워드
- 저자 : ( Rajendra Dev Bhatt ) (검색결과 2 건)
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( Rajendra Dev Bhatt ),( Prabodh Risal ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1
Aims: Acute organophosphorus poisoning (OP) is a major problem worldwide causing thousands of deaths annually. Self ingestion of these organophosphorus poisoning and deaths taking place in low income countries is very high. And the major causes of this self ingestion of OP are mainly domestic violence, poverty, illiteracy, mental disorder etc. The main aim of this study is to explore the association of liver function test in OP poisoning subjects which is commonly requested from emergency department. Methods: It is a hospital based observational study where 103 (79 females and 24 males) patients seen in emergency room of University Hospital in the duration of two year. Pre-structured sociodemographic questionnaire along with selected biochem ical parameters for OP ingested patients were analyzed where random blood sugar, electrolytes, renal function test, liver func tion test and cholinesterase was performed in fully automated chemistry analyzers. According to patients relatives, known case of chronic alcohol consumer, liver disease, diabetes, hy pertension, and renal failure were excluded. Descriptive analysis was done to explore the association of these biochemical pa rameters among OP ingested patients. Results: Dyselectrolytemia and low level of cholinesterase is very common observation among OP subject but there was no statistical significant association was found in liver function test of these subjects except Aspartate transaminase enzyme which was slightly increased only in 32% and mild hypoalbunemia was found in 22.3% subjects. Conclusions: This study suggested that requesting liver func tion test for acute OP patients from emergency department may be financial burden for family of OP subjects rather than clinical benefits, however large sample sized multicenter study is essential.
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( Pragya Bhatt ),( Madhusudan Subedi ),( Rajendra Dev Bhatt ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1
Aims: Ethnomedicine is a system of therapy using natural agents and their derivatives to treat ailments by the ethnic communities. This study was aimed to analyze and record the knowledge of ethnomedicinal plants for treating liver disorders among tharu tribe of far western Nepal. Methods: A descriptive cross sectional observational study was conducted in ten Tharu Tribe inhabited villages of Kanchan pur district of Far West Nepal. Rapid Rural Appraisal (RRA), ‘Semi-structured interviews and focus group discussions were employed to collect data from four Guruwas, the main tradi tional healer, as key informants, some knowledgeable persons, (but not Guruwas) as informants and some youths in Tharu tribes, categorizing them into three groups. The information shared was further discussed among all three groups. Results: This study enumerated an encouraging data of 39 plant species being used for the treatment of liver and related diseases by tharu community. Out of these, 9 plant species (8 families) were solely used for jaundice and biliary ailments.33 other plant species were also recorded for being used to cure digestive system related disorders which might be related to liver diseases.Fresh plants and their parts including leaves (max imum used), barks, fruits, flowers, roots, rhizome and latex in the form of juice, powder, decoction, and paste and pulverized were used and administered by oral route. Some dietary restric tions (no alcohol, less oil etc.) were also made during medica tion. Consult the Guruwas for traditional healing was found to be the first choice for jaundice in the selected community. Around 43% jaundiced get well with traditional treatment while rest of the patients visited hospitals. Conclusions: A proper documentation and further elaborated research for ethnomedicinal plant being used by this tribal peo ple is essential to understand the mechanism of action of these plants for jaundice and other liver diseases.
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