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      • Poster Session : PS 0270 ; Gastroenterology : Automated System for Diagnostics of Pyloroduodenal Stenosis

        ( Pavel Kosenko ),( Sergej Vavrinchuk ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Methods: Object of study-patients with ulcerative PDS. Studied event-electrophysiological parameters of gastrointestinal motility. Study method-electrogastroenterography. We studied the values of baseline and stimulated electric activity of sections of gastrointestinal tract (GIT). GIT motility was stimulated using standard food load - 200 ml of water, and 100 g of white bread. Statistic processing of data-cluster analysis and discriminative analysis. Results: We examined 65 patients with ulcerative PDS. Based on the received data we detected the changes in GIT motility in patients with PDS indicating the dissociation between evacuator and motor disorder. It was confi rmed by the presence of transient types of motorics from compensation to decompensation, which were selected into separate groups on the basis of cluster and discriminative analyses. EGEG values after organ-preserving surgeries were statistically signifi cantly different from pre-operation values and had direct correlation relation to detected pre-operation values. Detected particularities show the need for separate accounting of evacuator and motor GITdisorders when selecting the method for surgical intervention. Using the discriminative analysis of the received data we created mathematic models for prediction of motor-evacuator disorder, including the detected transient types of gastric motorics with total percent of proper observation classifi cations in the relevant group 96. 2%. Conclusions: On the basis of the resulting mathematical models and databases for PEGEGparameters we created the computer program-System of Support for Decision Making in Defi ning the Compensation Degree of Pyloroduodenal Stenosis. The program hasmodular structures and gives the user the following possibility: establishment of PDS diagnosis and determination of degree of its compensation; possibility to generate the plots of non-linear discriminative functions of different electrophysiological parameters together with depiction of individual parameters of patients; perform the update of database to adjust statistics.

      • Poster Session:PS 0213 ; Gastroenterology : Electrophysiological Characterization of Gastrointestinal Tract Motility in Patients with Axial Hiatal Hernia

        ( Viacheslav Matianin ),( Pavel Kosenko ),( Sergey Vavrinchuk ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Background: Evaluation of electrophysiological parameters of gastrointestinal tract motility in patients with axial hiatal hernia. Methods: Object of study is 20 patients with axial hiatal hernia. The studied phenomenon is electrophysiological indicators of gastrointestinal tract motility. The method of investigation is peripheral electrogastroenterography (PEGEG) with the help of “Gastroskan-HEV” device according to standard procedures. Static data processing is a discriminative analysis. Results: The analysis of peripheral electrogastroenterography (PEGEG) indicators for patients with axial hiatal hernia revealed statistically signifi cant changes of 22 indicators mainly due to changes of Pi, Pi/Ps, Pi/P(i +1) parameters and Krhythm. Signifi cant differences with the control group are revealed on basal and stimulated Pi, Pi/Ps, Pi/ P(i +1) parameters and Krhythm of stomach, duodenum and colon. There was a statistically signifi cant doubling in basal and stimulated values of Pi/P(i +1) of stomach / duodenum, indicating that there was a motor discoordination of gastroduodenal junction. Change in colon PEGEG indicators in our opinion has been associated with the presence of neuro-refl ex connections between the stomach and colon, and manifested in a signifi cant increase in the stimulated Pi/Ps colon index. During the discriminative analysis of PEGEG indicators the patients with axial hiatal hernia were distributed in a separate from the control group with 97.7% accuracy. Conclusions: The discriminative analysis of PEGEG indicators in patients with axial hiatal hernia revealed signifi cant changes of 22 PEGEG indicators mostly of stomach and colon, refl ecting violations of discoordination of gastrointestinal motor activity with a high degree of difference from the group of healthy individuals.

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