Isoetin 5'-Methyl Ether, A Cytotoxic Flavone from Trichosanthes kirilowii

Rahman, Md. Aziz Abdur,Moon, Surk-Sik Korean Chemical Society 2007 Bulletin of the Korean Chemical Society Vol.28 No.8

Bioassay-directed fractionations of the seed extracts of Trichosanthes kirilowii, have resulted in the isolation of two new compounds, 2-(4-hydroxy-3-methoxyphenyl)-3-(2-hydroxy-5-methoxyphenyl)-3-oxo-1-propanol (2) and isoetin 5'-methyl ether (5,7,2',4'-tetrahydroxy-5'-methoxyflavone) (3), together with two known compounds, 7-hydroxychromone (1) and 5,7,4'-trihydroxy-3',5'-dimethoxyflavone (tricin, 4). Their structures were characterized by spectroscopic analysis such as 2D-NMR, HRTOFMS, and UV. Compound 3 showed cytotoxicity against human lung cancer cell line A549, human skin melanoma SK-Mel-2, and mouse melanoma B16F1, with IC50 of 0.92, 8.0, and 7.23 μg/mL, respectively.

Antimicrobial Phenolic Derivatives from Dendranthema zawadskii var. latilobum Kitamura (Asteraceae)

Md. Aziz Abdur Rahman,Surk-Sik Moon 대한약학회 2007 Archives of Pharmacal Research Vol.30 No.11

A phytochemical study on the root of Dendranthema zawadskii var. latilobum Kitamura, using a series of silica gel column chromatography and reversed phase C-18 HPLC chromatography, led to the isolation of (1S, 2S)-1, 2, 3-trihydroxy-1-(3, 4-methylenedioxyphenyl)propane (1), 4- methoxycinnamic acid (2), acacetin (3) and caffeic acid methyl ester (4). The structures of these compounds were determined using spectroscopic analyses (UV, IR, HRTOFMS and NMR), with comparison of their spectral data with previously reported values. Compound 1 was isolated for the first time, with compounds 2 and 4 from this plant reported for the first time. The antibacterial and antifungal activities of the isolated compounds were measured using the disc diffusion method. Also, their cytotoxicities against the cancer cell lines, A549, B16F1 and SK-Mel-2, and brine shrimp lethalities were evaluated.

Antioxidant Polyphenol Glycosides from the Plant Draba nemorosa

Md. Aziz Abdur Rahman,문석식 대한화학회 2007 Bulletin of the Korean Chemical Society Vol.28 No.5

Bioassay-directed fractionation of Draba nemorosa led to the isolation of two new phenolic glycosides, 1-O-(sinapoyl)-glucitol (2) and 1,3-disinapoylgentiobiose (5) along with five known phenolic glycosides (1, 3, 4, 6, and 7). Their structures were characterized based on spectroscopic methods (2D NMR, HRTOFMS, IR, and UV). The isolated compounds showed antioxidant activities (IC50) in the range of 14-98 mM which were estimated by DPPH radical-scavenging assay.

Antimicrobial Phenolic Derivatives from Dendranthema zawadskii var. latilobum Kitamura (Asteraceae)

Rahman, Md. Aziz Abdur,Moon, Surk-Sik 대한약학회 2007 Archives of Pharmacal Research Vol.30 No.11

A phytochemical study on the root of Dendranthema zawadskii var. latilobum Kitamura, using a series of silica gel column chromatography and reversed phase C-18 HPLC chromatography, led to the isolation of (1S, 2S)-1, 2, 3-trihydroxy-1-(3, 4-methylenedioxyphenyl)propane (1), 4-methoxycinnamic acid (2), acacetin (3) and caffeic acid methyl ester (4). The structures of these compounds were determined using spectroscopic analyses (UV, IR, HRTOFMS and NMR), with comparison of their spectral data with previously reported values, Compound 1 was isolated for the first time, with compounds 2 and 4 from this plant reported for the first time. The antibacterial and antifungal activities of the isolated compounds were measured using the disc diffusion method. Also, their cytotoxicities against the cancer cell lines, A549, B16F1 and SK-Mel-2, and brine shrimp lethalities were evaluated.

Isoetin 5'-Methyl Ether, A Cytotoxic Flavone from Trichosanthes kirilowii

Md. Aziz Abdur Rahman,문석식 대한화학회 2007 Bulletin of the Korean Chemical Society Vol.28 No.8

Bioassay-directed fractionations of the seed extracts of Trichosanthes kirilowii, have resulted in the isolation of two new compounds, 2-(4-hydroxy-3-methoxyphenyl)-3-(2-hydroxy-5-methoxyphenyl)-3-oxo-1-propanol (2) and isoetin 5'-methyl ether (5,7,2',4'-tetrahydroxy-5'-methoxyflavone) (3), together with two known compounds, 7-hydroxychromone (1) and 5,7,4'-trihydroxy-3',5'-dimethoxyflavone (tricin, 4). Their structures were characterized by spectroscopic analysis such as 2D-NMR, HRTOFMS, and UV. Compound 3 showed cytotoxicity against human lung cancer cell line A549, human skin melanoma SK-Mel-2, and mouse melanoma B16F1, with IC50 of 0.92, 8.0, and 7.23 mg/mL, respectively.

A genome-wide approach to the systematic and comprehensive analysis of LIM gene family in sorghum (Sorghum bicolor L.)

Md. Abdur Rauf Sarkar,Salim Sarkar,Md Shohel Ul Islam,Fatema Tuz Zohra,Shaikh Mizanur Rahman Korea Genome Organization 2023 Genomics & informatics Vol.21 No.3

The LIM domain-containing proteins are dominantly found in plants and play a significant role in various biological processes such as gene transcription as well as actin cytoskeletal organization. Nevertheless, genome-wide identification as well as functional analysis of the LIM gene family have not yet been reported in the economically important plant sorghum (Sorghum bicolor L.). Therefore, we conducted an in silico identification and characterization of LIM genes in S. bicolor genome using integrated bioinformatics approaches. Based on phylogenetic tree analysis and conserved domain, we identified five LIM genes in S. bicolor (SbLIM) genome corresponding to Arabidopsis LIM (AtLIM) genes. The conserved domain, motif as well as gene structure analyses of the SbLIM gene family showed the similarity within the SbLIM and AtLIM members. The gene ontology (GO) enrichment study revealed that the candidate LIM genes are directly involved in cytoskeletal organization and various other important biological as well as molecular pathways. Some important families of regulating transcription factors such as ERF, MYB, WRKY, NAC, bZIP, C2H2, Dof, and G2-like were detected by analyzing their interaction network with identified SbLIM genes. The cis-acting regulatory elements related to predicted SbLIM genes were identified as responsive to light, hormones, stress, and other functions. The present study will provide valuable useful information about LIM genes in sorghum which would pave the way for the future study of functional pathways of candidate SbLIM genes as well as their regulatory factors in wet-lab experiments.

Antioxidant Polyphenol Glycosides from the Plant Draba nemorosa

Rahman, Md. Aziz Abdur,Moon, Surk-Sik Korean Chemical Society 2007 Bulletin of the Korean Chemical Society Vol.28 No.5

Bioassay-directed fractionation of Draba nemorosa led to the isolation of two new phenolic glycosides, 1-O- (sinapoyl)-glucitol (2) and 1,3-disinapoylgentiobiose (5) along with five known phenolic glycosides (1, 3, 4, 6, and 7). Their structures were characterized based on spectroscopic methods (2D NMR, HRTOFMS, IR, and UV). The isolated compounds showed antioxidant activities (IC50) in the range of 14-98 mM which were estimated by DPPH radical-scavenging assay.

Investigation on Selective Mechanization for Wet Season Rice Cultivation in Bangladesh

Islam, AKM Saiful,Islam, Md Tariqul,Rahman, Md Shakilur,Rahman, Md Abdur,Kim, Youngjung Korean Society for Agricultural Machinery 2016 바이오시스템공학 Vol.41 No.4

Purpose: This study aimed to evaluate the profitability of four selective mechanization systems in rice cultivation. Methods: Field experiments were conducted in the farmers' field during the wet season (June to November) of 2015 in Bangladesh. Mechanization systems were applied to evaluate four different selective levels (treatment) in eleven consequent operations. Seedlings were raised in a traditional seedbed and trays for manual and mechanical transplanting, respectively. Land preparation, irrigation, fertilizer, pesticide, carrying, and threshing and cleaning operations were performed using the same method in all the experimental plots. The mechanical options in the transplanting, weeding, and harvesting operations were changed. The mechanization systems were $S_1$ = hand transplanting + hand weeding + harvesting by sickle, $S_2$ = mechanical transplanting + Bangladesh Rice Research Institute (BRRI) weeder + reaper, $S_3$ = mechanical transplanting + BRRI power weeder + reaper, and $S_4$ = mechanical transplanting + herbicide + reaper. This experiment was performed in a randomized complete block design with four replications. Power tiller, rice transplanter, BRRI weeder, BRRI power weeder, self-propelled reaper, BRRI open drum thresher, and BRRI winnower were used in the respective operations. Accordingly, the techno-economic performances of the different technologies were calculated and compared with those of the traditional system. Results: The mechanically transplanted plot produced 6-10% more yield than the hand transplanted plot because of the use of tender-aged seedlings. Mechanical transplanting reduced 61% labor and 18% cost compared to manual transplanting. The BRRI weeder, BRRI power weeder, and herbicide application reduced 74, 91, and 98% labor, respectively. The latter also saved 72, 63, and 82% cost, respectively, compared to hand weeding. Herbicide application reduced the substantial amount of labor and cost in the weeding operation. Mechanical harvesting also saved 96% labor and 72% cost compared to the traditional method of harvesting using sickle. Selective mechanization saved 15-17% input cost compared to the traditional method of rice cultivation. Conclusions: Mechanical transplanting with the safe use of herbicide and harvesting by reaper is the most cost- and labor-saving operation. The method might be the recommended set of selective mechanization for enhancing productivity.

Investigation on Selective Mechanization for Wet Season Rice Cultivation in Bangladesh

( Akm Saiful Islam ),( Md Tariqul Islam ),( Md Shakilur Rahman ),( Md Abdur Rahman ),( Youngjung Kim ) 한국농업기계학회 2016 바이오시스템공학 Vol.41 No.4

Purpose: This study aimed to evaluate the profitability of four selective mechanization systems in rice cultivation. Methods: Field experiments were conducted in the farmers` field during the wet season (June to November) of 2015 in Bangladesh. Mechanization systems were applied to evaluate four different selective levels (treatment) in eleven consequent operations. Seedlings were raised in a traditional seedbed and trays for manual and mechanical transplanting, respectively. Land preparation, irrigation, fertilizer, pesticide, carrying, and threshing and cleaning operations were performed using the same method in all the experimental plots. The mechanical options in the transplanting, weeding, and harvesting operations were changed. The mechanization systems were S₁ = hand transplanting + hand weeding + harvesting by sickle, S₂ = mechanical transplanting + Bangladesh Rice Research Institute (BRRI) weeder + reaper, S₃ = mechanical transplanting + BRRI power weeder + reaper, and S₄ = mechanical transplanting + herbicide + reaper. This experiment was performed in a randomized complete block design with four replications. Power tiller, rice transplanter, BRRI weeder, BRRI power weeder, self-propelled reaper, BRRI open drum thresher, and BRRI winnower were used in the respective operations. Accordingly, the techno-economic performances of the different technologies were calculated and compared with those of the traditional system. Results: The mechanically transplanted plot produced 6-10% more yield than the hand transplanted plot because of the use of tender-aged seedlings. Mechanical transplanting reduced 61% labor and 18% cost compared to manual transplanting. The BRRI weeder, BRRI power weeder, and herbicide application reduced 74, 91, and 98% labor, respectively. The latter also saved 72, 63, and 82% cost, respectively, compared to hand weeding. Herbicide application reduced the substantial amount of labor and cost in the weeding operation. Mechanical harvesting also saved 96% labor and 72% cost compared to the traditional method of harvesting using sickle. Selective mechanization saved 15-17% input cost compared to the traditional method of rice cultivation. Conclusions: Mechanical transplanting with the safe use of herbicide and harvesting by reaper is the most cost- and labor-saving operation. The method might be the recommended set of selective mechanization for enhancing productivity.

Evaluation of Mechanical Transplanter in Unpuddled Transplanting of Wet Season Rice in Sandy Loam Soil

Akm Saiful Islam,Muhammad Abdur Rahman,Md. Anwar Hossen,Tahmid Hossain Ansari,Biswajit Karmakar 한국토양비료학회 2014 한국토양비료학회 학술발표회 초록집 Vol.2014 No.6