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RISS 인기검색어
- 검색키워드
- 저자 : ( Jih Ye Cha ) (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
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HCC : PE-062 ; The Radiotherapy on HCC in caudate lobe
( Hyun Jung Kim ),( Jih Ye Cha ),( Hae Ok Pyun ),( Jin Sil Seong ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.1
Background: Hepatocelluar carcinoma (HCC) in caudate lobe has poor prognosis and is challenging to treat with surgery, radiofreqeuncy ablation (RFA), transcatheter arterial embolization (TACE) because of its unique anatomic location. This study was designed to assess the efficacy and safety of radiotherapy (RT) for HCC in the caudate lobe. Methods: Between January 1996 and August 2011, 58 patients with HCC in caudate lobe were treated with RT. Fifty cases were treated after the failure of previous RFA or TACE. Eight patients were treated as definitive aim. Most of the patients were treated with RT alone (44%) while the others were treated with RT with intra-arterial (34%) or systemic chemotherapy (15%), RT after TACE (7%) within 1 month. Median radiation dose was 45Gy (range, 30.6 - 80 Gy) in 25 fractions. The tumor response was determined by CT scans at post-RT 3 months. Results: The median follow-up period after RT was 10.6 months (range, 1 ? 93 months). The 1 year- and 2 year-local control rates were 73.5% and 47.7%, respectively, and 1 yearand 2 year-overall survival rates were 53.8% and 40.4%, respectively. Complete response was achieved in two patients. In-field local control was achieved in 70% of patients. During the follow-up, 14 patients (24%) developed intra-hepatic metastases and eight patients (13%) developed extra-hepatic metastases: lung, distant lymph nodes, bone, and brain. Seven patients developed grade 1 nausea or anorexia during RT. There were no grade 3 or greater treatment-related toxicities. Conclusions: Radiotherapy appears to be an effective and feasible treatment modality for HCC in caudate lobe.
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HCC : PE-063 ; The therapeutic efficacy of radiotherapy for HCC in caudate lobe
( Hyun Jung Kim ),( Jih Ye Cha ),( Hae Ok Pyun ),( Jin Sil Seong ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.1
Background: Hepatocellular carcinoma (HCC) in caudate lobe has poor prognosis due to unsatisfactory effect with currenttreatment including surgery, radiofrequency ablation (RFA), transcatheter arterial embolization (TACE) because of its unique anatomic location. This study was designed to assess the efficacy and safety of radiotherapy (RT) for HCC in the caudate lobe. Methods: Between January 1996 and August 2011, 58 patients with HCC in caudate lobe were treated with RT. Fifty patients were treated after the failure of previous RFA or TACE and 8 patients, as definitive aim. Most of the patients were treated with RT alone (44%) while the others were treated with RT with intra-arterial (34%) or systemic chemotherapy (15%), RT after TACE (7%) within 1 month. Median radiation dose was 45Gy (range, 30.6 - 80 Gy) in 25 fractions. The tumor response was determined by CT scans at post-RT 3 months. Results: The median follow-up period after RT was 10.6 months (range, 1?93 months). The 1- and 2- year local control rates were 73.5% and 47.7%, respectively, and 1- and 2- year overall survival rates were 53.8% and 40.4%, respectively. Complete response was achieved in two patients. In-field local control was achieved in 70% of patients. During the follow-up, 14 patients (24%) developed intra-hepatic metastases and eight patients (13%) developed extra-hepatic metastases: lung, distant lymph nodes, bone, and brain. Seven patients developed grade 1 nausea or anorexia during RT. There were no grade 3 or above treatment-related toxicities. Conclusions: Radiotherapy appears to be an effective and feasible treatment modality for HCC in caudate lobe.
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