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RISS 인기검색어
- 검색키워드
- 저자 : ( Hiroto Habatu ) (검색결과 2 건)
- 무료
- 기관 내 무료
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( Soo Hyun Bae ),( Young Ju Jung ),( Hiroto Habatu ),( Araki Tetsuro ),( Gary M Hunninghake ),( Jinwoo Song ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: Prevalence and long term signifi cance of interstitial lung abnormalities (ILA) in Asian population remain unclear. Methods: This study included 334 subjects (males, 87.1 %; mean age, 48.2 yrs) who presented at AMC health screening center between 2003 and 2013 and had pairedchest CT of more than 10 year intervals. ILA was scored on baseline CT with a 3-point scale [0 = no evidence of ILA, 1 = equivocal for ILA, 2 = ILA] using a sequential reading method and categorized as centrilobular, subpleural, mixed and radiographic interstitial lung disease type. Temporal change was evaluated by side by side comparison (no change, improvement or progression). Association between ILA and clinical parameters was studied. Results: ILA was present in 7 subjects (2.1 %) at initial screening (score 0 in 44.6 %, score 1 in 53.3 %). The pattern was subpleural in 3 (42.9 %) and mixed in 4 (57.1 %) of the 7 participants. Those with ILA were signifi cantly older (mean age: 61.1 vs. 46.7 yrs, p < 0.001) and had lower lung function (FVC, 3.42 L vs. 4.03 L, p = 0.042; FEV1, 2.68 L vs. 3.27 L, p = 0.024) and BMI (21.5 vs. 24.6, p = 0.05) than those without. At follow-up CT scan of those with ILA (n=7), 2 (28.6 %) were improved and 2 (28.6%) were progressed. ILA was newly detected in 4 (2.7 %) of the 149 subjects who had no ILA on initial CT scan. Age was independent risk factor (HR 1.291; 95% CI, 1.059-1.574, p = 0.011) of ILA development. Conclusions: ILA is not uncommon in Asian population and a third showed progression on follow-up. ILA was associated with older ages indicating that ILA could be an aging process.
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( Soo Hyun Bae ),( Young Ju Jung ),( Hiroto Habatu ),( Araki Tetsuro ),( Gary M Hunninghake ),( Jin Woo Song ) 대한결핵 및 호흡기학회 2014 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.118 No.-
Background: Prevalence and long term significance of interstitial lung abnormalities (ILA) in Asian population remain unclear. Methods: This study included 334 subjects (males, 87.1 %; mean age, 48.2 yrs) who presented at AMC health screening center between 2003 and 2013 and had paired chest CT of more than 10 year intervals. ILA was scored on baseline CT with a 3-point scale [0 = no evidence of ILA, 1 = equivocal for ILA, 2 = ILA] using a sequential reading method and categorized as centrilobular, subpleural, mixed and radiographic interstitial lung disease type. Temporal change was evaluated by side by side comparison (no change, improvement or progression). Association between ILA and clinical parameters was studied. Results: ILA was present in 7 subjects (2.1 %) at initial screening (score 0 in 44.6 %, score 1 in 53.3 %). The pattern was subpleural in 3 (42.9 %) and mixed in 4 (57.1 %) of the 7 participants. Those with ILA were significantly older (mean age: 61.1 vs. 46.7 yrs, p < 0.001) and had lower lung function (FVC, 3.42 L vs. 4.03 L, p = 0.042; FEV1, 2.68 L vs. 3.27 L, p = 0.024) and BMI (21.5 vs. 24.6, p = 0.05) than those without. At follow-up CT scan of those with ILA (n=7), 2 (28.6 %) were improved and 2 (28.6%) were progressed. ILA was newly detected in 4 (2.7 %) of the 149 subjects who had no ILA on initial CT scan. Age was independent risk factor (HR 1.291; 95% CI, 1.059-1.574, p = 0.011) of ILA development. Conclusions: ILA is not uncommon in Asian population and a third showed progression on follow-up. ILA was associated with older ages indicating that ILA could be an aging process.
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