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      • KCI등재

        Effects of Brain Mechanical Properties on Child Head Responses under Linear Load

        Shihai Cui,Yue Chen,Haiyan Li,Lijuan He,Shijie Ruan 대한의용생체공학회 2016 Biomedical Engineering Letters (BMEL) Vol.6 No.2

        Purpose It is usually difficult to obtain the accurate mechanicalproperties of pediatric brain and skull because of the absenceof pediatric cadaver experiments. The goal of this work is todiscuss how different brain mechanical properties influencepediatric head response. Methods A validated finite element model of a 3-year-oldchild head with detailed anatomical structures was used toparametrically investigate the effects of mechanical propertieson child head. Taguchi orthogonal method was adopted todecrease the numbers of the simulation under direct impactload. Results With the increase of the skull elastic modulus, thecoup pressure decreases significantly (P < 0.001) whereasthe contrecoup pressure (P < 0.001) and maximum vonMises stress of skull (P < 0.001) increase significantly. Withthe increase of the short-time shear modulus of brain tissue,maximum shear stress of brain tissue (P < 0.001) increasessignificantly whereas the maximum principal strain (P < 0.01)decreases significantly. Conclusions Both Elastic modulus of skull and linearviscoelastic material parameters of brain tissues have statisticallysignificant effects on impact responses of child head. Differentmaterial parameters can lead to a great difference on impactresponses of child head.

      • KCI등재

        Nematicidal activity against Aphelenchoides besseyi and Ditylenchus destructor of three biflavonoids, isolated from roots of Stellera chamaejasme

        Hui Jin,Haiyan Cui,Xiaoyan Yang,Lihong Xu,Xudong Li,Rentao Liu,Zhiqiang Yan,Xiuzhuang Li,Weili Zheng,Yuhui Zhao,Xiaoxia Song,Lihua Zhong,Anxiang Su,Bo Qin 한국응용곤충학회 2018 Journal of Asia-Pacific Entomology Vol.21 No.4

        Aphelenchoides besseyi and Ditylenchus destructor can cause serious problems for a number of important agricultural crops and vegetables. In this study, the ethanol extract of Stellera chamaejasme L. roots showed strong nematicidal activity against Aphelenchoides besseyi and Ditylenchus destructor. By using a bioactivity-driven fractionation, three biflavonoids were isolated from the extract and their structures were identified by mass and nuclear magnetic resonance spectral data. Nematicidal activity bioassays revealed that isoneochamaejasmin A had the strongest nematicidal activity against A. besseyi and D. destructor with LC 50 values of 2.32 and 0.18 mM at 72 h, respectively. Chamaejasmenin B displayed weaker nematicidal activity against A. besseyi with an LC 50 value of 3.94 mM at 72 h. Neochamaejasmin B induced the lowest mortality against D. destructor with an LC 50 values of 15.6 mM at 72 h. These results suggested that the kind and position of substitutions and the relative configuration of 2-H/3-H and 2”-H/3”-H could be considered as important factors responsible for the nematicidal activity of these purified C-3/C-3″ biflavonoids.

      • KCI등재

        Facile Atmospheric Generation of Water Radical Cations via TiO2-Nanoneedle Arrays for Aromatic Hydrocarbon Detection Based on Corona Discharge

        Dongbo Mi,Jinhaojie Cui,Siliang Kuang,Xiaofeng Dong,Haiyan Lu 대한화학회 2021 Bulletin of the Korean Chemical Society Vol.42 No.3

        Water radical cations, (H2O)n+?, have attracted considerable attention owing to their potential practical applications in analytical chemistry, structural chemistry, radiotherapy, and radiochemistry. Recently, atmospheric pressure chemical ionization has emerged as a versatile method for direct mass spectrometric analysis. Usually, H3O+ is the major proton donor during ionization and only the pseudo molecular ion peaks, instead of molecular ions are detected. In this work, (H2O)2+? ions with high oxidizability and reactivity were generated using hydrothermally grown TiO2 nanoneedle arrays in combination with a linear ion trap mass spectrometer under low operating voltage and applied to the direct mass spectrometric analysis of a mixture of volatile aromatic hydrocarbons. (H2O)2+? ions were generated with a high absolute ion current of up to 1.07???105?counts/s at atmospheric pressure. Using the generated (H2O)2+? as the primary ion permitted the tandem mass spectrometric analysis of a mixed vapor sample of aromatic hydrocarbons.

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        Diversity and Functions of Endophytic Fungi Associated with Roots and Leaves of Stipa purpurea in an Alpine Steppe at Qinghai-Tibet Plateau

        ( Xiaoyan Yang ),( Hui Jin ),( Lihong Xu ),( Haiyan Cui ),( Aiyi Xin ),( Haoyue Liu ),( Bo Qin ) 한국미생물 · 생명공학회 2020 Journal of microbiology and biotechnology Vol.30 No.7

        Stipa purpurea is a unique and dominant herbaceous plant species in the alpine steppe and meadows on the Qinghai-Tibet Plateau (QTP). In this work, we analyzed the composition and diversity of the culturable endophytic fungi in S. purpurea according to morphological and molecular identification. Then, we investigated the bioactivities of these fungi against plant pathogenic fungi and 1- aminocyclopropane-1-carboxylate deaminase (ACCD) deaminase activities. A total of 323 fungal isolates were first isolated from S. purpurea, and 33 fungal taxa were identified by internal transcribed spacer primers and grouped into Ascomycota. The diversity of endophytic fungi in S. purpurea was significantly higher in roots as compared to leaves. In addition, more than 40% of the endophytic fungi carried the gene encoding for the ACCD gene. The antibiosis assay demonstrated that 29, 35, 28, 37 and 34 isolates (43.9, 53.1, 42.4, 56.1, and 51.5%) were antagonistic to five plant pathogenic fungi, respectively. Our study provided the first assessment of the diversity of culturedepending endophytic fungi of S. purpurea, demonstrated the potential application of ACCD activity and antifungal activities with potential benefits to the host plant, and contributed to high biomass production and adaptation of S. purpurea to an adverse environment.

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