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      • Poster Session : PS 0127 ; Cardiology : Risk Management of Cardiovascular Disease Through Milk Enriched with Sterols in a Young-Adult Population

        ( Yurrita Collado Luis ),( San Mauro Ismael ),( Cuadrado Marria Angeles ),( Hernandez Marta ),( Ciudad Maria Jose ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Backgournd: Hypercholesterolemia is one of the most relevant risk factors of cardiovascular diseasein spain, where. Aim to determine the effectiveness of a rich in phytosterols for reducing markers of cardiovascular disease Methods: A randomized, clinical controlled trial, double-blind crossover study. The sample was recruited from the University Hospital Clinico San Carlos in Madrid. The sterols were ingested through commercial milk, with two phases and three weeks respectively separated by a washout period of 2 weeks. At the beginning and end of each phase blood draws were performed. Taking 2 glasses of milk daily in administering them an amount of 2.7 g of plant sterols per day, for those subjects during the “milk of study “, and the same amount of skim milk, sterols, for placebo. Lipid profi le, hematology, was collected Results: Nineteen people completed the study of 34.68 years (± 6.91). The difference between baseline and fi nal scores were 19.47 (± 29.10) mg / dl, 24.47 ( ± 30.68 ) mg / dl, 14.36 (± 44.16) mg / dl for LDL cholesterol, the TC and TG, respectively, representing a decrease of 12.21 (± 18.70) %, 10.44 (± 12.88) % and 7.04 (± 35.77) % decrease for LDL-C, TC and TG, respectively. Without considerable changes in HDLc. There are signifi cant differences between placebo and milk with sterols for LDL (p=0.009) and Ct (p=0.003). Similar data have been reported by many groups in other matrices, and to a lesser extent milk, with similar decreases in lipid markers. Conclusions: As is evident, sterols supplied in a functional food, such as milk, can be a strategy for non- pharmacological treatment of hypercholesterolemia and therefore a tool for cardiovascular risk reduction globally.

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