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        A Novel Least Square and Image Rotation based Method for Solving the Inclination Problem of License Plate in Its Camera Captured Image

        ( Changcheng Wu ),( Hao Zhang ),( Jiafeng Hua ),( Sha Hua ),( Yanyi Zhang ),( Xiaoming Lu ),( Yichen Tang ) 한국인터넷정보학회 2019 KSII Transactions on Internet and Information Syst Vol.13 No.12

        Recognizing license plate from its traffic camera captured images is one of the most important aspects in many traffic management systems. Despite many sophisticated license plate recognition related algorithms available online, license plate recognition is still a hot research issue because license plates in each country all round the world lack of uniform format and their camera captured images are often affected by multiple adverse factors, such as low resolution, poor illumination effects, installation problem etc. A novel method is proposed in this paper to solve the inclination problem of license plates in their camera captured images through four parts: Firstly, special edge pixels of license plate are chosen to represent main information of license plates. Secondly, least square methods are used to compute the inclined angle of license plates. Then, coordinate rotation methods are used to rotate the license plate. At last, bilinear interpolation methods are used to improve the performance of license plate rotation. Several experimental results demonstrated that our proposed method can solve the inclination problem about license plate in visual aspect and can improve the recognition rate when used as the image preprocessing method.

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        Saponins from Panax japonicus ameliorate age-related renal fibrosis by inhibition of inflammation mediated by NF-κB and TGF-β1/Smad signaling and suppression of oxidative stress via activation of Nrf2-ARE signaling

        Yan Gao,Ding Yuan,Liyue Gai,Xuelian Wu,Yue Shi,Yumin He,Chaoqi Liu,Changcheng Zhang,Gang Zhou,Chengfu Yuan 고려인삼학회 2021 Journal of Ginseng Research Vol.45 No.3

        Background: The decreased renal function is known to be associated with biological aging, of which the main pathological features are chronic inflammation and renal interstitial fibrosis. In previous studies, we reported that total saponins from Panax japonicus (SPJs) can availably protect acute myocardial ischemia. We proposed that SPJs might have similar protective effects for aging-associated renal interstitial fibrosis. Thus, in the present study, we evaluated the overall effect of SPJs on renal fibrosis. Methods: Sprague-Dawley (SD) aging rats were given SPJs by gavage beginning from 18 months old, at 10 ㎎/㎏/d and 60 ㎎/㎏/d, up to 24 months old. After the experiment, changes in morphology, function and fibrosis of their kidneys were detected. The levels of serum uric acid (UA), β2-microglobulin (β2-MG) and cystatin C (Cys C) were assayed with ELISA kits. The levels of extracellular matrix (ECM), matrix metalloproteinases (MMPs), tissue inhibitors of metalloproteinases (TIMPs), inflammatory factors and changes of oxidative stress parameters were examined. Results: After SPJs treatment, SD rats showed significantly histopathological changes in kidneys accompanied by decreased renal fibrosis and increased renal function; As compared with those in 3-month group, the levels of serum UA, Cys C and β2-MG in 24-month group were significantly increased (p < 0.05). Compared with those in the 24-month group, the levels of serum UA, Cys C and β2-MG in the SPJ-H group were significantly decreased. While ECM was reduced and the levels of MMP-2 and MMP-9 were increased, the levels of TIMP-1, TIMP-2 and transforming growth factor-β1 (TGF-β1)/Smad signaling were decreased; the expression level of phosphorylated nuclear factor kappa-B (NF-κB) was down-regulated with reduced inflammatory factors; meanwhile, the expression of nuclear factor erythroid 2-related factor 2-antioxidant response element (Nrf2-ARE) signaling was aggrandized. Conclusion: These results suggest that SPJs treatment can improve age-associated renal fibrosis by inhibiting TGF-β1/Smad, NFκB signaling pathways and activating Nrf2-ARE signaling pathways and that SPJs can be a potentially valuable anti-renal fibrosis drug.

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