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[P493] A case of terra firma-forme dermatosis
( Inho Bae ),( Chanho Na ),( Bongseok Shin ),( Minsung Kim ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1
Terra Firma-Forme Dermatosis (TFFD) is a disease that occurs frequently in adolescence, and is clinically form of dusty, hyperpigmented plaques. TFFD was first reported by Duncan in the 1970s and there are no clear causative factors to date, but there are hypotheses that lesions are made by accumulation of melanin, sebum, sweat and scales. We report a 10-year-old female who presented with hyperpigmented skin lesions on both jaws and around the neck from 2 years ago. The patient was in normal sanitary condition and the lesions were not removed after bathing. The patient had no medical history, weight gain and preceding skin disease. Dermoscopic findings were observed brown papules with an irregular shape and no abnormal findings of melanocytes, blood vessels were shown. We performed KOH test around the neck and result showed normal. The lesions were completely removed by rubbing with an alcohol sponge. TFFD was diagnosed with the above findings, and no recurrence was observed for 6 months. Herein we report a case of TFFD occurring in a young female that successfully treated with alcohol scrubbing. Therefore when we faced with atypical pigmentation disorder, TFFD shoud be considered.
A case of trichotillomania successfully treated with N-acetylcysteine
( Yeason Lee ),( Inho Bae ),( Bongseok Shin ),( Chanho Na ),( Minsung Kim ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1
Trichotillomania is a medical condition caused by the patient himself by pulling out of own hair, resulting in a perceptible hair loss pattern that frequently is associated with other psychiatric processes. Generally has a chronic course in most patients, and a challenging therapeutical management. There are several available options for treatment, but the clinical response is not satisfactory in many patients. Recently, N-acetylcysteine, a glutamate modulator, has shown efficacy in the treatment of trichotillomania and other compulsive behaviors, and is considered a new alternative in the management of this condition. We describe a patient with trichotillomania successfully treated with N-acetylcysteine.. The patient was a 14-year-old man that attended at our outpatient Department of Dermatology with 12*10cm sized hair loss on vertex. He presented bizarre hair loss appearance with broken and cork-screwed hairs. The hairs had different lengths on dermoscopic examination. Complete regrowth was observed after introducing N-acetylcysteine 800 mg/day during 2 months and 1600 mg/day during 3months.
[P180] A case of bullous prurigo pigmentosa in a healthy woman
( Inho Bae ),( Chanho Na ),( Bongseok Shin ),( Minsung Kim ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1
Prurigo pigmentosa is a rare type of inflammatory dermatosis characterized by symmetrical pruritic erythematous papules that normally resolve with reticular pigmentation. The rash occurs mainly on the central back, scapular, chest, clavicular and nuchal regions. But vesicular or bullous forms have been reported rarely. Some studies have shown that the possibility of an association between prurigo pigmentosa and fasting, pregnancy, ketonemia and diabetic mellitus. A 20-year-old female presented with vesicobullae upon erythematous papuloplaques on the back without preceding disease. She had erythematous lesions on her back for 2 years, and bullous lesions were accompanied 4 months ago. A skin biopsy revealed an intraepidermal bullae filled with neutrophils, perivascular lymphocytes and eosinophils infiltration involving dermis. The clinical and histological features of our case are compatible with bullous prurigo pigmentosa. She treated with doxycycline 100mg twice a day and topical steroid cream. After 2 weeks, the skin lesion improved and post-inflammatory reticulated hyperpigmented patches remained. Herein we present a rare case of bullous prurigo pigmentosa occurring in a healthy woman that successfully treated with doxycycline.
A case of merkel cell carcinoma with squamous cell carcinoma treated with postoperative radiotherapy
( Yeason Lee ),( Yoonsoo Kim ),( Bongseok Shin ),( Chanho Na ),( Minsung Kim ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1
Merkel cell carcinoma is a rare neuroendocrinal tumor of the skin. It is noted for its typical aggressive nature unlike other skin tumors. Because of the rarity, the treatment is not standardised. Radiotherapy in the postoperative setting is effective in improving the loco regional control. A case of merkel cell carcinoma treated with postoperative radiotherapy is reported. A 89 year old man presented with a left forearm swelling measuring 7.0*9.0cms of 1 year duration. The growth was proliferative and bled on touch. Biopsy from the growth revealed a malignant small round cell tumor with features of merkel cell tumor. Histopathology revealed a merkel cell carcinoma with the overlying squamous epithelium showing basisquamous carcinoma. The tumor was positive for CD56, CK, CK20and Synaptophysin. Chest and Abdomino-pelvic CT scan did not show abnormal findings. The tomor was excised up to the muscle fascia with positive resection margin and could not repair the lesion because of the size and site. The patient underwent post-operative radiotherapy on the lesion for 8 weeks (25 times, total 5, 000 cGy). After 1month of final radiotherapy, the wound was fully healed without significant complications.