Three new iridoids named as pediverticilatasin A – C (1 – 3, resp.), together with five known iridoids (4 – 8, resp.) were isolated from the whole plants of Pedicularis verticillata. The structures of three new compounds were identified as (1S,7...
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https://www.riss.kr/link?id=O120640440
Ming‐Hui Shao ; Wei Dai ; Si‐Wen Yuan ; Yan Lu ; Dao‐Feng Chen ; Qi Wang
2018년
-
1612-1872
SCIE;SCOPUS
학술저널
n/a-n/a [※수록면이 p5 이하이면, Review, Columns, Editor's Note, Abstract 등일 경우가 있습니다.]
0
상세조회0
다운로드다국어 초록 (Multilingual Abstract)
Three new iridoids named as pediverticilatasin A – C (1 – 3, resp.), together with five known iridoids (4 – 8, resp.) were isolated from the whole plants of Pedicularis verticillata. The structures of three new compounds were identified as (1S,7...
Three new iridoids named as pediverticilatasin A – C (1 – 3, resp.), together with five known iridoids (4 – 8, resp.) were isolated from the whole plants of Pedicularis verticillata. The structures of three new compounds were identified as (1S,7R)‐1‐ethoxy‐1,5,6,7‐tetrahydro‐7‐hydroxy‐7‐methylcyclopenta[c]pyran‐4(3H)‐one (1), (1S,4aS,7R,7aS)‐1‐ethoxy‐1,4a,5,6,7,7a‐hexahydro‐7‐hydroxy‐7‐methylcyclopenta[c]pyran‐4‐carboxylic acid (2), (1S,4aS,7R,7aS)‐1‐ethoxy‐1,4a,5,6,7,7a‐hexahydro‐7‐hydroxy‐7‐methylcyclopenta[c]pyran‐4‐carbaldehyde (3). Their structures were elucidated on the basis of spectroscopic methods and compared with the NMR spectra data in the literature. All compounds were evaluated for their anti‐complementary activity on the classical pathway of the complement system in vitro. Among which, compounds 1, 3, and 6 exhibited anti‐complementary effects with CH50 values ranging from 0.43 to 1.72 mm, which are plausible candidates for developing potent anti‐complementary agents.