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      Nuclear receptors : from structure to the clinic

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      https://www.riss.kr/link?id=M14058731

      • 저자
      • 발행사항

        Cham : Springer, 2015

      • 발행연도

        2015

      • 작성언어

        영어

      • 주제어
      • DDC

        572.8 판사항(23)

      • ISBN

        9783319187280 (alk. paper)
        3319187287 (alk. paper)

      • 자료형태

        일반단행본

      • 발행국(도시)

        스위스

      • 서명/저자사항

        Nuclear receptors : from structure to the clinic / edited by Ian J. McEwan, Raj Kumar.

      • 형태사항

        xi, 236 p. : ill. ; 25 cm.

      • 일반주기명

        Includes bibliographical references and index.
        Twenty-five Years of Nuclear Receptor Structure Analysis: From the Laboratory to the Clinic / Iain J. McEwan and Raj Kumar -- Part I. ALLOSTERIC REGULATION AND NUCLEAR RECEPTOR COMPLEX DYNAMICS. Corticosteroid Receptors / Peter J. Fuller, Jun Yang, and Morag J. Young -- Glucocorticoid Receptor Structure and Function / Raj Kumar and Iain J. McEwan -- What Determines the Difference in DNA Binding Between the Androgen and the Glucocorticoid Receptors? / Vanessa Dubois [and 10 others] -- Allosteric Regulation and Intrinsic Disorder in Nuclear Hormone Receptors / Jordan T. White [and 4 others] -- Structural Analyses of Ordered and Disordered Regions in Ecdysteroid Receptor / Marek Orlowski [and 8 others] -- Structural Analysis of Heterodimeric Nuclear Receptors / Brice Beinsteiner and Dino Moras -- Part II. NUCLEAR RECEPTOR CO-REGULATORY PROTEIN INTERACTIONS. Primate-specific Multi-functional Androgen Receptor Coregulator and Proto-oncogene Melanoma Antigen-A11 (MAGE-A11) / Elizabeth M. Wilson -- Assembly and Regulation of Nuclear Receptor Corepressor Complexes / Christopher J. Millard and John W.R. Schwabe -- Part III. TAKING NUCLEAR RECEPTOR STRUCTURE INTO THE CLINIC -- Thinking Outside the Box: Alternative Binding Sites in the Ligand Binding Domain of Nuclear Receptors / Nerea Gallastegui and Eva Estébanez-Perpiñá -- Selective Estrogen Receptor Modulators (SERMs) and Selective Androgen Receptor Modulators (SARMs) / Ramesh Narayanan and James T. Dalton.

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      목차 (Table of Contents)

      • CONTENTS
      • Twenty-five Years of Nuclear Receptor Structure Analysis : From the Laboratory to the Clinic / Iain J. McEwan ; Raj Kumar = 1
      • Part Ⅰ Allosteric Regulation and Nuclear Receptor Complex Dynamics
      • Corticosteroid Receptors / Peter J. Fuller ; Jun Yang ; Morag J. Young = 17
      • Glucocorticoid Receptor Structure and Function / Raj Kumar ; Iain J. McEwan = 41
      • CONTENTS
      • Twenty-five Years of Nuclear Receptor Structure Analysis : From the Laboratory to the Clinic / Iain J. McEwan ; Raj Kumar = 1
      • Part Ⅰ Allosteric Regulation and Nuclear Receptor Complex Dynamics
      • Corticosteroid Receptors / Peter J. Fuller ; Jun Yang ; Morag J. Young = 17
      • Glucocorticoid Receptor Structure and Function / Raj Kumar ; Iain J. McEwan = 41
      • What Determines the Difference in DNA Binding Between the Androgen and the Glucocorticoid Receptors? / Vanessa Dubois ; Christine Helsen ; Liesbeth Clinckemalie ; Lien Spans ; Michaël Laurent ; Leen Antonio ; Thomas Van den Broeck ; Stefan Prekovic ; Steven Joniau ; Dirk Vanderschueren ; Frank Claessens = 59
      • Allosteric Regulation and Intrinsic Disorder in Nuclear Hormone Receptors / Jordan T. White ; Hesam N. Motlagh ; Jing Li ; E. Brad Thompson ; Vincent J. Hilser = 73
      • Structural Analyses of Ordered and Disordered Regions in Ecdysteroid Receptor / Marek Orłowski ; Piotr Dobryszycki ; Anna Zoglowek ; Joanna Pieprzyk ; Katarzyna Bielska ; Beata Greb-Markiewicz ; Małgorzata Kozłowska ; Aneta Tarczewska ; Andrzej Ożyhar = 93
      • Structural Analysis of Heterodimeric Nuclear Receptors / Brice Beinsteiner ; Dino Moras = 119
      • Part Ⅱ Nuclear Receptor Co-regulatory Protein Interactions
      • Primate-Specific Multi-Functional Androgen Receptor Coregulator and Proto-Oncogene Melanoma Antigen-All(MAGE-A11) / Elizabeth M. Wilson = 137
      • Assembly and Regulation of Nuclear Receptor Corepressor Complexes / Christopher J. Millard ; John W. R. Schwabe = 155
      • Part Ⅲ Taking Nuclear Receptor Structure into the Clinic
      • Thinking Outside the Box : Alternative Binding Sites in the Ligand Binding Domain of Nuclear Receptors / Nerea Gallastegui ; Eva Estébanez-Perpiñá = 179
      • Selective Estrogen Receptor Modulators(SERMs) and Selective Androgen Receptor Modulators(SARMs) / Ramesh Narayanan ; James T. Dalton = 205
      • Index = 229
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      Nuclear Receptors: From Structure to the Clinic

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