腎疾患에서의 Cellulose Acetate 電氣泳動分劃에 對한 硏究 = Studies of the renal diseases on the cellulose acetate electrophoretic fractions of serum proteins

다국어 초록 (Multilingual Abstract)

Cellulose acetate electrophoretic studies of renal diseases were performed and the following results were obtained:
1 ) The mean values for the electrophoretic fractions of serum protein in nephrotic syndrome were 1.18±0.48 gm/100ml (28.65±8.03%), 0.25±0.19 gn/100ml (5.05±3.17%) 1.146±0.57 gn/100 ml(35.95±12.83%),0.72±0.28 gn/100 ml(17.32±5.39%), and 0.56±0.21 gm/100ml(13.45±4.47%), respectively, for the albumin, α_(1)-,α_(2)-, β-, and γ-globulin fractions. It was found that decreased both albumin 2.11 gm/100 ml(19.17%), and γ-globulin, 0.94 gm/100ml(7.83%), fractions were more marked than in control groups. While α_(2)-globulin fraction was markedly increased, 0.7 gm/100 ml(25.3%), to compare in control group.
2 ) The correlation coefficient between albumin and α_(2)-globulin fractions in nephrotic syndrome was γ=-0.84and regression equation was y=-1.34x+74.40.
3 ) The A/G ratio was markedly reversed as 0.40±0.16.
4 ) The mean values for the electrophoretic fractions of serum proteins in nonnephrotic syndrome, i.e., acute and chronic glomerulonephritis, renal failure, pyelon-ephritis, and renal stones, were 2.35±0.59 gm/100 ml(40.74±8.54%), 0.27±0.13 gn/100 ml(4.65±1.98%), 0.78±0.25 gm/100ml(13.30±2.84%) 0.93±0.28 gm/100ml (15.75±4.33%), and 1.43±0.58 gm/100ml (24.14±8.14%), respectively, for the albumin, α_(1)-, α_(2)-, β-, and γ-globulin fractions. Is was found that decreased albumin and increased α_(1)-globulin fractions were marked than in control group.
5 ) Is the biochemical data in nephrotic syndrome it was found that serum cholesterol was increased 2.5 times than in control group. In non-nephrotic syndrome group it was found that increased concentration of serum K and markedly increased concentration of serum creatinine(4.5 times) and BUN(3 times) were shown.

목차 (Table of Contents)

• Abstract = 1
• 목차 = 3
• 서론 = 4
• 대상 및 방법 = 4
• 결과 및 고찰 = 6
• 결론 = 12
• 참고문헌 = 14