신생아 제대혈의 혈청 Cortisol치와 Glucose치에 관한 연구

다국어 초록 (Multilingual Abstract)

We have studied the serum cortisol levels of cord blood in newborn infants(40 cases)and the serum cortisol levels of maternal blood at parturition(40 cases). And we also studied the serum glucose levels of cord blood in 25 cases of newborn infant.For the purpose of analysis,the study objects were divided into two groups:normal vaginal delivery(35 cases) and cesarian section delivery(5 cases).
Serum cortisol levels were measured by the method of radioimmunoas-say(Amerlex CortisolRiAKit, Amersham International Limited,UK) and serum glucose levels were measured by o-Toluidine method(Glucose Reagent and Standard Set. B, Japan).
The following results were obtained.
1. The mean serum cortisol levels of cord blood in 40 cases of the newborn infant were 13.1±8.3㎍/100㎖ and the mean serum cortisol levels of maternal blood in 40 cases of the mother were 49.1±28.0㎍/100㎖. In comparison of serum cortisol levels for the newborn infants and the mothers,the serum cortisol levels of the newborn infant were significantly lower than those of the mothers(p＜0.01).
2. The correlation of the serum cortisol levels of cord blood in the newborn infants and the serum cortisol levels of the mothers were not significant(r=0.18).
3. The mean serum cortisol levels of cord blood in 35 cases of noral vaginal delivery and in 5 cases of cesarian section delivery were 14.1±8.2㎍/100㎖ and 4.9±2.2㎍/100㎖ respectively. In comparison of serum cortisol levels cord blood between two groups, the serum cortisol levels of cord blood in cesarian section delivery were significantly lower than those of cord blood in normalvaginal del ivery(p＜0.01).
4. There observed no significant diurnal variations on the serum cortisol levels which were related to the time of delivery in the newborn infants and the mothers.
5. In comparison of the serum cortisol levels of cord blood for the gestational age in normal newborn infants,there were no significant differences between the newborn infants under 40 weeks of gestation and the newborn infants over 40 weeks of gestation.
6. The mean serum glucose levels of cord blood in 25 cases of normal newborn infant were 87.64±1.2㎎/100㎖. The correlation between serum glucose and cortisol levels of cord blood in the normal newborn infants were not significant(r=0.042).

목차 (Table of Contents)

• 목차 = 1
• 도표목차 = 2
• Abstract = 3
• Ⅱ. 서론 = 5
• Ⅲ. 연구대상 및 검사방법 = 6
• Ⅳ. 연구성적 = 8
• Ⅴ. 고찰 = 15
• Ⅵ. 결론 = 20
• 참고문헌 = 22