The deoxysugar biosynthetic gene cluster was cloned from S. argillaceous, the producer of mithramycin. The gene cluster composed of the homologous gene of actI and the dehydratase. The actI homologous gene was located in downstream about 10 kb from th...
The deoxysugar biosynthetic gene cluster was cloned from S. argillaceous, the producer of mithramycin. The gene cluster composed of the homologous gene of actI and the dehydratase. The actI homologous gene was located in downstream about 10 kb from the dehydratase gene. The pLS210 and pLS600 subcloned from pLS cosmid were partially sequenced and analyzed.