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      KCI등재 SCIE SCOPUS

      한국인과 중국인에서 인삼과 서양삼 복용후 전신 증상 - 이중맹검 무작위배정 임상시험 -

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      https://www.riss.kr/link?id=A75963044

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      다국어 초록 (Multilingual Abstract)

      In East-South Asia it has been said that ginseng(Panax ginseng) induces flushing and epistaxis, whereas American ginseng(Panax quinquefolius) dosen't. This study was designed to find out if ginseng really could increase flushing and epistaxis, compare...

      In East-South Asia it has been said that ginseng(Panax ginseng) induces flushing and epistaxis, whereas American ginseng(Panax quinquefolius) dosen't. This study was designed to find out if ginseng really could increase flushing and epistaxis, compared with American ginseng. Double-blind randomized controlled trials on general symptom, such as flushing and epistaxis, of ginseng and American ginseng in Koreans and Chinese were performed by questionnaire. There was no significant accident or improvement in Koreans. But in Chinese dried mouth was significantly observed in placebo group and chest discomfort was significant in placebo group and American ginseng(4 years) group. In addition in Chinese chest discomfort was significantly observed in American ginseng(4 years) group and American ginseng(6 years) group. It was revealed that ginseng might not increase flushing and epistaxis.

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      목차 (Table of Contents)

      • Abstracts
      • 서론
      • 재료 및 방법
      • 결과 및 고찰
      • 요약
      • Abstracts
      • 서론
      • 재료 및 방법
      • 결과 및 고찰
      • 요약
      • 감사의 말씀
      • 인용문헌
      • 부록
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      참고문헌 (Reference)

      1 "The control of acute cisplatin-induced emesis a comparative study of granisetron and a combination regimen of high-dose metoclopramide and dexamethasone. Br. J. Cancer 68" 176-180, 1993

      2 "Studies on absorption excretion and metabolism of ginseng saponins. VII. Comparison of the decomposition modes of ginsenoside Rb1 and Rb2 in the digestive tract of rats. Chem. Pharm. Bull. 39" 400-404, 1991

      3 "Properties of ginseng saponin inhibition of catecholamine secretion in bovine chromaffin cells. Eur. J. Pharmacol. 341" 341 : 139-144, 1998

      4 "Probing the role of a conserved M1 proline residue in 5-hyroxytryptamine3 receptor gating. Mol. Pharmacol. 57" 57 : 1114-1122, 2000

      5 "Ondansetron versus metoclopramide in the treatment of postoperative nausea and vomiting. Anesth. Analg. 85" 85 : 395-399, 1997

      6 "Multiple sites of action for noncompetitive blockers on acetylcholine receptor rich membrane fragments from Torpedo marmorata. Biochemistry 22" 3112-3127, 1983

      7 "Metabolism of ginseng saponins ginsenosides by human intestinal flora. J. Trad. Med. 11" 241-245, 1994

      8 "Luminal and non-luminal non-competitive inhibitor binding sites on the nicotinic acetylcholine receptor. Mol. Membr. Biol. 13" 13 : 1-17, 1996

      9 "Local anesthetic and histrionicotoxin are allosteric inhibitors of the acetylcholine receptor. J. Biol. Chem. 257" 8106-8114, 1982

      10 "In vivo antimetastatic action of ginseng protopanaxadiol saponins is based on their intestinal bacterial metabolites after oral administration. Oncol. Res. 9" 9 : 411-417, 1997

      1 "The control of acute cisplatin-induced emesis a comparative study of granisetron and a combination regimen of high-dose metoclopramide and dexamethasone. Br. J. Cancer 68" 176-180, 1993

      2 "Studies on absorption excretion and metabolism of ginseng saponins. VII. Comparison of the decomposition modes of ginsenoside Rb1 and Rb2 in the digestive tract of rats. Chem. Pharm. Bull. 39" 400-404, 1991

      3 "Properties of ginseng saponin inhibition of catecholamine secretion in bovine chromaffin cells. Eur. J. Pharmacol. 341" 341 : 139-144, 1998

      4 "Probing the role of a conserved M1 proline residue in 5-hyroxytryptamine3 receptor gating. Mol. Pharmacol. 57" 57 : 1114-1122, 2000

      5 "Ondansetron versus metoclopramide in the treatment of postoperative nausea and vomiting. Anesth. Analg. 85" 85 : 395-399, 1997

      6 "Multiple sites of action for noncompetitive blockers on acetylcholine receptor rich membrane fragments from Torpedo marmorata. Biochemistry 22" 3112-3127, 1983

      7 "Metabolism of ginseng saponins ginsenosides by human intestinal flora. J. Trad. Med. 11" 241-245, 1994

      8 "Luminal and non-luminal non-competitive inhibitor binding sites on the nicotinic acetylcholine receptor. Mol. Membr. Biol. 13" 13 : 1-17, 1996

      9 "Local anesthetic and histrionicotoxin are allosteric inhibitors of the acetylcholine receptor. J. Biol. Chem. 257" 8106-8114, 1982

      10 "In vivo antimetastatic action of ginseng protopanaxadiol saponins is based on their intestinal bacterial metabolites after oral administration. Oncol. Res. 9" 9 : 411-417, 1997

      11 "Evolutionary history of the ligand-gated on channel superfamily of receptors. Trends Neurosci. 18" 18 : 121-127, 1995

      12 "Effects of ginsenosides active components of ginseng on nicotinic acetylcholine receptors expressed in Xenopus oocytes. Eur. J. Pharmacol. 442" 442 : 37-45, 2002

      13 "Effects of ginsenoside Rg2 on human neuronal nicotinic acetylcholine receptors. J. Pharmacol. Exp. Ther. 301" 301 : 1052-1059, 2002

      14 "Differential Effect of Ginsenoside Metabolites on the 5-HT3A Receptor-Mediated Ion Current in Xenopus Oocytes. Mol. Cells" 17 : 51-56, 2004

      15 "Clinical studies of the vitamins. Jpn. Soc. Inter. Med. 54" 989-1006, 1965

      16 "Cisplatin increases the release of 5-hydroxytryptamine from the isolated vascularly perfused small intestine of the guineapig-involvement of 5-HT3 receptors. Naunyn-Schmiedeberg's Arch. Pharmacol. 344" 5 143-149, 1991

      17 "Blockade of 5-hydroytryptamine3 receptors prevents cisplatin-induced but not motion- or xylazine-induced emesis in the cat. Pharmacol. Biochem. Behav. 32" 207-210, 1989

      18 "Animal models in the study of vomiting. Can. J. Physiol. Pharmacol. 68" 260-268, 1990

      19 "An intestinal bacterial metabolite of ginseng protopanaxadiol saponins has the ability to induce apoptosis in tumor cells. Biochem. Biophys. Res. Commun. 249" 249 : 725-730, 1998

      20 "Advances in the control of chemotherapy-induced emesis. Ann. Oncol. 3 Suppl. 3" 47-50, 1992

      21 "A comparison of the efficacy and patient satisfaction of ondansetron versus droperidol as antiemetics for elective outpatient surgical procedures. S3A-409 and S3A-410 Study Groups. Anesth. Analg. 86" 86 : 731-738, 1998

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      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2023 평가예정 해외DB학술지평가 신청대상 (해외등재 학술지 평가)
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      2007-01-01 평가 등재 1차 FAIL (등재유지) KCI등재
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      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 3.97 1.04 2.93
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