Primary malignant melanoma of esophagus is rare and its symptoms are similar to those of squamous cell carcinoma. In general, this tumor tends to be polypoid with smooth intact overlying mucosa or be pediculated and irregular. Microscopically, charact...
Primary malignant melanoma of esophagus is rare and its symptoms are similar to those of squamous cell carcinoma. In general, this tumor tends to be polypoid with smooth intact overlying mucosa or be pediculated and irregular. Microscopically, characteristic features are junctional lenti- ginous growth pattern and tendency to expand and fill the submucosa without invading the muscularis. Primary malignant melanoma should be radiologically differentiated with unusual esophageal tumor, particularly if the lesion is polypoid. Because of the patentially widespread intramural component, surgical treatment requires a radical procedures with a far greater margin than for the usual squamous cell carcinoma. Despite these measures, however the prognosis is poor, with a 5 year survival of 4.2%. It is usually fatal within one year. The case of a 64-year-old man with esophageal malignant melanoma is described, and review of the llterature in presented related studies. (Korean J Gastroenterol 1995;27:245 - 250)