Three cases of pulmonary and/or intestinal tuberculosis in adolescents

다국어 초록 (Multilingual Abstract)

Since the tuberculosis (TB) in adolescents has unique clinical characteristics, special attention should be paid to this age group. Adolescents are more susceptible to developing TB disease and more likely to have cavitary pulmonary disease. Also, adolescent patients with TB more frequently present with extrapulmonary disease. We report three adolescents with active pulmonary and/or intestinal TB: one had pulmonary and intestinal TB, another had a pulmonary TB, and the third exclusively had an intestinal TB. Diagnosis was confirmed by pathologic examination of the lung and/or intestines. All three patients were treated successfully without complication. A brief review of the literature has been included.

국문 초록 (Abstract)

최근 결핵 유병률이 청소년기에 다시 증가하고 있으며, 이 시기의 결핵은 성인이나 어린 소아와는 다른 임상적 특징을 가지고 있다. 결핵 감염에서 질병으로 쉽게 발전되거나, 폐외 결핵의 발생 빈도가 높고, 폐결핵에서 공동이 잘 생기며, 항결핵제에 내성이 있는 경우가 많아 치료실패율이 높기 때문에 조기 진단과 치료를 위해 의료진의 보다 적극적인 관심과 노력이 필요하다. 저자들은 최근 청소년에서 조직검사로 확진된 폐 및 폐외 결핵 3례를 경험하였기에 보고하는 바이다.

참고문헌 (Reference)

1 Hanekom WA, "Vitamin A status and therapy in childhood pulmonary tuberculosis" 131 : 925-927, 1997

2 Lobato MN, "Tuberculosis in children and adolescents: California, 1985 to 1995" 17 : 407-411, 1998

3 Wilcox WD, "Tuberculosis in adolescents: A case commentary" 33 : 258-262, 1994

4 de Pontual L, "Tuberculosis in adolescents: A French retrospective study of 52 cases" 25 : 930-932, 2006

5 Didilescu C, "The epidemiological profile and current evolutionary trends in tuberculosis in adolescents (15-19 years old) in the capital" 46 : 193-199, 1997

6 Nemir RL, "Perspectives in adolescent tuberculosis: Three decades of experience" 78 : 399-405, 1986

7 Rianthavorn P, "Medication non-adherence in the adolescent renal transplant recipient: a clinician's viewpoint" 9 : 398-407, 2005

8 Onwubalili JK, "Malnutrition among tuberculosis patients in Harrow, England" 42 : 363-366, 1988

9 McIntosh ED, "Extrapulmonary tuberculosis in children" 158 : 735-740, 1993

10 Morisky DE, "Behavioral interventions for the control of tuberculosis among adolescents" 116 : 568-574, 2001

11 Kam A, "Active tuberculosis among adolescents in Toronto, Canada: Clinical features and delays in diagnosis" 26 : 355-356, 2007

12 Akcam M, "Abdominal tuberculosis in adolescents: Difficulties in diagnosis" 26 : 122-126, 2005

13 Davies PD, "A possible link between vitamin D deficiency and impaired host defence to Mycobacterium tuberculosis" 66 : 301-306, 1985

14 Karyadi E, "A double-blind, placebo-controlled study of vitamin A and zinc supplementation in persons with tuberculosis in Indonesia: Effects on clinical response and nutritional status" 75 : 720-727, 2002