Methotrexate has been used to treat refractory psoriasis for many years. Despite its well-established clinical efficacy, drawbacks to methotrexate usage include a number of deleterious effects including hepatotoxicity, bone marrow suppression, and int...
Methotrexate has been used to treat refractory psoriasis for many years. Despite its well-established clinical efficacy, drawbacks to methotrexate usage include a number of deleterious effects including hepatotoxicity, bone marrow suppression, and interstitial pneumonitis.
We experienced a case of liver cirrhosis m patient with active psoriasis receiving long-term ora1 methotrexate therapy, and reported this case with review of literature.