Micropipette for Dispensing Sub-nanoliter Volume in Discrete Manner

다국어 초록 (Multilingual Abstract)

We report a microdispenser that can meter and mix sub-nanoliter liquids in a discrete quantity. Our device is based on the structural stopping valve used in passive dispensers. A vent channel was proposed, designed for the autonomous pausing of a metered liquid segment and the seamless joining of the subsequent segments. While the previous microfluidic devices could meter only a single drop [2-4], lacking in mixing multiple segments, our approach enables the metering/mixing of different liquids in a discrete ratio. This module will find applications in bio-engineering and pharmaceutical research including large-scale cell differentiation experiment and drug discovery platforms.

목차 (Table of Contents)

• Abstract
• 1. Introduction
• 2. Working Principle
• 3. Fabrication
• 4. Experimental Results
• 5. Discussion and Summary
• Acknowledgement
• 참고문헌