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      건선환자에서 Methotrexate 복용 후 발생한 구진성 발진 1예 = A case of acute papular eruption associated with methotrexate in patient with psoriasis

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      https://www.riss.kr/link?id=A105987254

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      다국어 초록 (Multilingual Abstract)

      Methotrexate remains a cornerstone in the treatment of severe psoriasis and psoriatic arthritis. To date, several methotrexate induced mucocutaneous adverse reactions have been reported and there are few case reports of papular eruption induced by met...

      Methotrexate remains a cornerstone in the treatment of severe psoriasis and psoriatic arthritis. To date, several methotrexate induced mucocutaneous adverse reactions have been reported and there are few case reports of papular eruption induced by methotrexate in patient with psoriasis. A 70-year-old man visited our clinic with multiple erythematous papules on his trunk. The lesions developed 4 weeks after methotrexate treatment and disappeared after drug cessation in about 1 week. Herein, we report a rare case of acute papular eruption induced by methotrexate in patient with psoriasis.

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      참고문헌 (Reference)

      1 김영지, "한국인 피부과환자에서 Methotrexate 치료효과 및 부작용" 대한피부과학회 52 (52): 237-243, 2014

      2 Kaye O, "The frequency of cutaneous vasculitis is not increased in patients with rheumatoid arthritis treated with methotrexate" 23 : 253-257, 1996

      3 Kumar B, "Short-term methotrexate therapy in psoriasis: a study of 197 patients" 41 : 444-448, 2002

      4 Lebwohl M, "Psoriasis treatment: traditional therapy" 64 : 83-86, 2005

      5 Goerttler E, "Methotrexate-induced papular eruption in patients with rheumatic diseases: a distinctive adverse cutaneous reaction produced by methotrexate in patients with collagen vascular diseases" 40 : 702-707, 1999

      6 Mebazaa A, "Methotrexate-induced papular eruption following treatment of psoriasis" 42 : 138-141, 2008

      7 Warren RB, "Methotrexate for psoriasis in the era of biological therapy" 33 : 551-554, 2008

      8 Litt JZ, "Litt's Drug Eruption Reference Manual Including Drug Interactions" CRC press 401-404, 2009

      9 Saurat JH, "Efficacy and safety results from the randomized controlled comparative study of adalimumab vs. methotrexate vs. placebo in patients with psoriasis (CHAMPION)" 158 : 558-566, 2008

      1 김영지, "한국인 피부과환자에서 Methotrexate 치료효과 및 부작용" 대한피부과학회 52 (52): 237-243, 2014

      2 Kaye O, "The frequency of cutaneous vasculitis is not increased in patients with rheumatoid arthritis treated with methotrexate" 23 : 253-257, 1996

      3 Kumar B, "Short-term methotrexate therapy in psoriasis: a study of 197 patients" 41 : 444-448, 2002

      4 Lebwohl M, "Psoriasis treatment: traditional therapy" 64 : 83-86, 2005

      5 Goerttler E, "Methotrexate-induced papular eruption in patients with rheumatic diseases: a distinctive adverse cutaneous reaction produced by methotrexate in patients with collagen vascular diseases" 40 : 702-707, 1999

      6 Mebazaa A, "Methotrexate-induced papular eruption following treatment of psoriasis" 42 : 138-141, 2008

      7 Warren RB, "Methotrexate for psoriasis in the era of biological therapy" 33 : 551-554, 2008

      8 Litt JZ, "Litt's Drug Eruption Reference Manual Including Drug Interactions" CRC press 401-404, 2009

      9 Saurat JH, "Efficacy and safety results from the randomized controlled comparative study of adalimumab vs. methotrexate vs. placebo in patients with psoriasis (CHAMPION)" 158 : 558-566, 2008

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