급격한 전신 전이 양상을 보인 편도에 발생한 소세포암종 1예 = A Case of Small Cell Carcinoma in Tonsil with Aggressive Systemic Metastasis

다국어 초록 (Multilingual Abstract)

Small cell carcinoma is a highly malignant tumor that is most commonly of bronchogenic origin and well recognized for its aggressive clinical behavior. Extrapulmonary small cell carcinoma is rare, accounting for 2-5% of all small cell carcinomas, and the head and neck origin of small cell carcinoma is especially uncommon. Small cell carcinomas arising in the head and neck have been reported to date in larynx, salivary glands, palate, base of tongue, sinonasal tract, and tonsil. Only a few cases of small cell carcinoma of the tonsil have been reported worldwide, and it is the first case to be reported here in Korea. With the report of this case, we suggest that systemic chemotherapy should be considered for all patients with small cell carcinoma in tonsil because of its high incidence of extensive local invasion and metastasis. (Korean J Otorhinolaryngol-Head Neck Surg 2008;51:825-8)

참고문헌 (Reference)

1 Kimmelman CP, "Small cell carcinomas of the head and neck" 91 (91): 708-712, 1983

2 Bawa R, "Small cell carcinoma of the tonsil" 113 (113): 328-333, 1995

3 Rejowski JE, "Small cell carcinoma of the nose and paranasal sinuses" 90 (90): 516-517, 1982

4 Renner G, "Small cell carcinoma of the head and neck: A review" 34 (34): 3-14, 2007

5 Koss LG, "Small cell (oat cell) carcinoma of minor salivary gland origin" 30 (30): 737-741, 1972

6 Patterson SD, "Oat-cell carcinoma, primary in parotid gland" 9 (9): 77-82, 1985

7 Ferlito A, "Neuroendocrine neoplasms of the larynx: Advances in identification, understanding, and management" 42 (42): 770-788, 2006

8 Minna J, "Neoplasms of the lung, in : Harrison’s Principles of internal medicine" McGraw-Hill Book 1115-1123, 1987

9 Mineta H, "Immunohistochemical analysis of small cell carcinoma of the head and neck: A report of four patients and a review of sixteen patients in the literature with ectopic hormone production" 110 (110): 76-82, 2001

10 Crawford JN, "Gastrointestinal tract, in : Pathologic basis of disease" W.B.Saunders 842-845, 1984

11 Benito J, "Garcia N, Perez-Requena J. [Oat-cell carcinoma of the tongue: Report of a case]" 52 (52): 438-441, 2001

12 Abedi E, "Extrapulmonary oat-cell carcinoma of the tonsil" 66 (66): 112-115, 1987

13 Olofsson J, "Anaplastic small cell carcinoma of larynx. Case report" 81 (81): 284-287, 1972

14 Heimann R, "Anaplastic small cell (oat cell) carcinoma of the tonsils: Report of two cases" 14 (14): 67-74, 1989