Effects of hyaluronic acid injected using the mesogun injector with stamp-type microneedle on skin hydration = Effects of hyaluronic acid injected using the mesogun injector with stamp-type microneedle on skin hydration

다국어 초록 (Multilingual Abstract)

Background: There is an increasing interest in the use of hyaluronic acid (HA) fillers in skin rejuvenation beyond its conventional use which is supplementing decreased dermis volume and filling deep wrinkles.
Objectives: This study aimed to evaluate the efficacy and safety of a novel device (Dermashine® balanceTM) that injects HA into the dermis using a stamp-type microneedle for maintenance of hydration and elasticity of the skin.
Methods: A single-center randomized double-blinded parallel-group clinical study involving 60 participants was conducted. The subjects were randomized to receive HA injections or a placebo 3 times across the face using an automatic intradermal injector. At 4, 8, and 12 weeks after the treatment, skin hydration was measured using a corneometer and skin elasticity was measured using a cutometer.
Results: The patients who received HA showed significantly greater skin hydration than those who received the placebo. However, a significant difference was not noted in skin elasticity between the groups. No severe adverse event was reported.
Conclusion: The results of this study suggest that intradermal supplementation of HA using mesogun multi-needle injector may be a safe and effective treatment for improving skin hydration.