Dextran Gel 의 분자구조 = Molecular Structure of Dextran Gel

다국어 초록 (Multilingual Abstract)

Dextran, a main constituent of Sephadex gel, is a linear homopolymer (polysaccharide) composed almost exclusively of the monomeric unit, α-D-glucopyranose, linked mainly by 1-6 glucosidic bonds. As a basic building block of dextran, the conformation of α-gentiobiose (6-0-α-D-glucopyranosyl-α-D-glucopyranose) in vacuum was studied by the technique of the consistent force field. We presented the procedures of identifying the position of each atoms in a reference coordinate system. The molecular structure of a Sephadex gel was simulated as two sets of cylinders: one for a unit of α-gentiobiose and the other for a cross-linking bridge. The structural dimension of a dextran gel (Sephadex G-25) was expressed by the radius and the length of those cylinders: a cylinder with a radius at 2.54 Å and a length of 5.61 Å for α-gentiobiose and a cylinder with a radius of 1.57 Å a length of 4.84 Å for the cross-linking bridge.