조산아에서 삼첨판막의 증식조직을 보인 칸디다성 심내막염 1례 -수술적 제거 및 항진균제 치료의 성공적 치험 = A Case of Candida Endocarditis with Vegetation on the Tricuspid Valve in a Preterm Infant

국문 초록 (Abstract)

저자들은 32＋2주의 미숙아로 중심정맥관을 통한 지속적인 항생제 투여와 정맥 영양을 공급받은 환아에서 진균성 심내막염이 병발하여 생후 72일경에 심초음파로 삼첨판 증식 조직이 발견되어 개심술로 종괴 제거와 술후 항진균제 투여로 완치된 예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

다국어 초록 (Multilingual Abstract)

Fungal endocarditis is a rare disease in infants, but it has been reported with increasing frequency among premature infants requiring neonatal intensive care. Congenital heart disease, prolonged intravenous catheterization, the use of intravenous alimentation, broad-spectrum antibiotics administration and narcotic addiction are risk factors. Candida endocarditis is an unusual but severe complication of systemic candidiasis. Its occurrence has been related to the placement of a central venous catheter with its tip close to or within the right atrium and persistent candidemia. Embolization to major blood vessels is a common complication of Candida endocarditis and repeated pulmonary emboli are suspected to be cause of the repeated episodes of circulatory shock which finally leads to death.
Thus, early diagnosis of Candida invasion and prevention of Candida endocarditis are essential for survival. We report a case of Candida endocarditis which was successfully managed with surgical removal and antifungal therapy.