한국 소아의 혈중 및 뇨중 아미노산 정상치에 관한 연구 = A Study on Normal Levels of Plasma and Urinary Amino Acid in Korean Children.

다국어 초록 (Multilingual Abstract)

1. We have analyzed the normal levels of the plasma and urinary amino acids in Korean children and infants for study of aminoacidopathy.
2. We have analyzed the plasma amino acids in 97 cases, and urinary amino acids in 113 cases. Mean age were 3.04 years and 3.16 years each other. (range 0∼15 years), Male were 58 cases (59.8%) and female were 39 cases (40.2%) in plasma analysis. Male were 66 cases (58.4%) and female were 47 cases (41.6%) in urine analysis.
3. The normal levels of plasma amino acids in Korean children follows as (unit : ㎛ol/L) : Phosphoserine 3.867∼9.129, Taurine 8.990∼177.217, Aspartic acid 2.081∼10.032, Hydroxyproline 7.040∼59.253, Threonine 24.928∼202.610, Serine 59.703∼198.781, Asparagine 46.906∼156.087, Glutamine 212.397∼729.105, Proline 56.285∼ 306.914, Glycine 72.813∼345.457, Alanine 101.395∼550.883, Citrulline 4.747∼40.953, αAminoadipic acid 2.695∼35.657, Valine 67.581∼349.002, Cystine 15.878∼50.157, Methionine 6.492∼39.708, Isoleucine 14.592∼ 104.550, Leucine 28.413∼188.301, Tyrosine 20.748∼118.937, Phenylalanine 29.173∼97.758, Ethanolamine 0.828∼19.536, Ornithine 15.519∼105.009, Tryptophan 11.781∼78.877, Lysine 49.186∼249.272, Histidine 25.134∼225.983, Arginine 18.517∼135.421, Glutamic acid 14.881∼131.162.
4. The normal levels of urinary amino acids in Korean children follows as (unit : ㎛ol/g·creatinine) : Phosphoserine 0.002∼0.733, Taurine 0∼3.998,
Phosphoethanolamine 0∼0.493, Aspartic acid 0∼0.673, Hydroxyproline 0∼0.923, Threonine 0∼1.014, Serine 0∼1.869, Asparagine 0∼1.122, Glutamine 0∼2.146, arcosine 0∼0.180, α－ Aminoadipic acid 0∼0.307, Proline 0∼1.099, Glycine 0∼5.315, Alanine 0∼1.641, Citrulline 0∼0.372, α－ Aminobutyric acid 0∼0.086, Valine 0∼0.243, Cystine 0∼0.546, Methionine 0∼0.264, Cystathionine 0∼0.139. Isoleucine 0∼0.238, Leucine 0∼0.337, Tyrosine 0.028∼0.789, Phenylalanine 0∼1.074, β－Alanine 0∼3.129, β－Amino－iso－butyric acid 0∼7.050, Homocystine 0∼0.026, r－Aminobutyric acid 0∼0.579, Ethanolamine 0∼2.885, Hydroxylysine 0∼0.285, Ornithine 0∼0.173, Tryptophan 0∼0.379, Lysine 0∼1.507, 1－Methylhisidine 0∼0.852, Histidne 0.290∼3.258, 3－Methylhistidine 0∼0.565, Anserine 0∼2.131, Carnosine 0∼1.184, Arginine 0∼0.173, Glutamic acid 0∼0.133.