Comparison of Predicted Exercise Capacity Equations in Adults Korean Subjects = Comparison of Predicted Exercise Capacity Equations in Adults Korean Subjects

다국어 초록 (Multilingual Abstract)

Background/Aims
Maximal oxygen uptake (VO2 max) is useful index for assessment of exercise capacity. There is no reference value of VO2 max for Koreans. The purpose of this study is to compare actual VO2 max and predicted VO2 max using exercise capacity equations.
Method
This is a retrospective study using data for 383 patients who underwent cardiopulmonary exercise test (CPET) with incremental maximal cycle ergometer test at Asan medical center from January, 2020 to May, 2021. Among subject, stage 1, 2 lung cancer patients with no dyspnea and healthy persons with complaints of dyspnea of 131 subjects who had maximal CPET was analyzed.
Results
The study population aged 66±10 with male predominance (74%). CPET Results were VO2 max (L/min) of 1.25±0.32, VO2 max (ml/kg/min) of 19.6±3.6, peak work rate (watts) of 93.6±25.4, peak heart rate (bpm) of 146±20, peak O2 pulse (ml/beat) of 9.1±3, ventilator efficiency of 34±4.1, peak respiratory rate 34±7, and peak breathing reserve (%) of 35±18. There was significant discordance between the measured VO2 max and predicted VO2 max when predicted by the Jones, Hansen, and Wasserman prediction equations developed by Caucasian population (P < 0.001). Agreement using Bland-Altman test between True VO2 max and predicted VO2 max was the best in Chinese equation (-0.15, 2SD = 0.46) compared to Jones (0.43, 2SD = 0.98), Hansen (0.42, 2SD = 0.69), and Wasserman (0.42, 2SD = 0.69) equations
Conclusions
The reference value and prediction equation from studies in which populations were primarily Caucasian may not be appropriate for Koreans. Since the mean difference is the lowest in Chinese equation, it is considered appropriate to use Chinese equation in the Korean adult population.