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      Small Bowel Infarction by Mesenteric Venous Thrombosis due to Methylenetetrahydrofolate Reductase Gene Mutation

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      https://www.riss.kr/link?id=A106987164

      • 저자

        In Young Park (Departments of 1Internal Medicine, 2Surgery, and 3Digestive Disease Center, Hallym University Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea) ;  Byoung Joo Do (Departments of 1Internal Medicine, 2Surgery, and 3Digestive Disease Center, Hallym University Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea) ;  Jae Sung Ahn (Departments of 1Internal Medicine, 2Surgery, and 3Digestive Disease Center, Hallym University Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea) ;  Jae Hyuk Lee (Departments of 1Internal Medicine, 2Surgery, and 3Digestive Disease Center, Hallym University Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea) ;  Jun Ho Park (Departments of 1Internal Medicine, 2Surgery, and 3Digestive Disease Center, Hallym University Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea) ;  Jin Gu Kang (Departments of 1Internal Medicine, 2Surgery, and 3Digestive Disease Center, Hallym University Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea) ;  Bo Kyung Yang (Departments of 1Internal Medicine, 2Surgery, and 3Digestive Disease Center, Hallym University Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea) ;  Hyoung Su Kim (Departments of 1Internal Medicine, 2Surgery, and 3Digestive Disease Center, Hallym University Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea)

      • 발행기관
      • 학술지명
      • 권호사항
      • 발행연도

        2014

      • 작성언어

        Korean

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      • 자료형태

        학술저널

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        112-115(4쪽)

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      다국어 초록 (Multilingual Abstract)

      Acute mesenteric venous thrombosis (MVT) is an uncommon form of intestinal ischemia with high mortality and usually occurs in the setting of preexisting comorbidities including thrombophilia and abdominal inflammatory conditions. Hyperhomocysteinemia ...

      Acute mesenteric venous thrombosis (MVT) is an uncommon form of intestinal ischemia with high mortality and usually occurs in
      the setting of preexisting comorbidities including thrombophilia and abdominal inflammatory conditions. Hyperhomocysteinemia
      has been known to be a risk factor for thromboembolism, often located on an unusual site. Considering that homocysteine metabolism
      is determined genetically to a high degree, a mutant of methylenetetrahydrofolate reductase (MTHFR) C677T causes hyperhomocysteinemia,
      leading to thrombophilia. Until now, there have been few reports of MVT associated with MTHFR gene mutation.
      We, herein, report a case of small bowel infarction associated with MVT by MTHFR gene mutation in an adult without any
      other risk factors of thrombophilia.

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