정신과에서 Carbamazepine의 사용 = Carbamazepine in Psychiatry

다국어 초록 (Multilingual Abstract)

Carbamazepine, known as anticonvulsant, has recently been reported to have therapeutic effect in psychiatric disorder. To investigate the use of Carbamazepine in psychiatry, author evaluate 26 patients with psychiatric disorders who had been improved with carbamazepine. The results were as follows :
1. Of 26 patients, bipolar disorder and organic affective disorder manic state were 17, schizophrenias were 4 and atypical psychosis, schizoaffective disorder, organic personality disorder, borderline personality disorder, dementia was 1, respectively.
2. The mean Carbamazepine dosage was 801.9 ± 379.1 mg, and the serum level of carbamazepine was 7.94 ± 2.49ug/ml of 26 patients.
3. Transient decrease of white blood cells in 3 patients and transient decrease of platelet in 2 appeared. 6 patients showed dry mouth, mild dizzness, nausea but they were recovered without specific measures.
Further study about the mechanism of action and psychotropic effect of carbamazepine in psychiatric disorder will be required and carbamazepine may prove to be a useful drug for diverse psychiatric disorders without specific side effects in the therapeutic dosage range