소뇌교각부 비청신경초종종양 환자의 임상특성과 예후분석 = Clinical Features and Outcomes in the Non-Acoustic Neuroma Tumors of Cerebellopontine Angle

다국어 초록 (Multilingual Abstract)

Non-acoustic tumours of the cerebellopontine angle differ from vestibular schwannomas in their prevalence, clinical features, operative management, and surgical outcome. The author analysed various clinical characteristics and surgical result of 24 non-acoustic tumor of cerebellopontine angle to determine their distinctive diagnostic features, the surgical difficulties and outcomes and follow-up results. Methods：A retrospective analysis of clinical notes identified 24 patients with non-acoustic tumours of the cereelopontine angle. Data were extracted regarding presenting clinical features, histopathotogical data after surgical resection, surgical morbidity and mortatity, and clinical outcome(mean 36 months follow up). Results：The study group comprised 12 meningiomas(50%), 7 epidermoid cysts(29%), 3 trigeminal schwannom, 1 primitive neuroectodermal tumor, and 1 meastatic tumor. In patients with meningiomas, symptoms differed considerably from patients presenting with vestibular schwannomas. Cerebellar signs were present in 30% and hearing loss in only 25%. After surgical resection, normal facial nerve function was preserved in 80% of cases. For the meningioma patients, the success rate of of operation(good result) was 90%, any cranial nerve deficit was combined in 10% of patient, and the mortality was 0%. In the epidermoid group, fifth, seventh, and eighth nerve deficits were present in 100%, 14%, and 14% respectively. There were no new postoperative facial palsies. There was one perioperative death from pneumonia and meningitis and the rest(85%) showed good oucome in epidermoid patient. Overall, there were no recurrences requiring reoperation. Conclusion：Patients with non-acoustic lesions of the cerebellopontine angle often present with different symptoms and signs from those found in patients with schwannomas. Hearing loss is less prevalent. Cerebellar signs and facial paresis are more common as presenting features. Non-acoustic tumours of cerebellopontine angle can usually be resected with facial nerve preservation.