최우수논문상 (모체태아의학) = Gestational weight gain is an important risk factor for excessive fetal growth

다국어 초록 (Multilingual Abstract)

Objective: To estimate the odds ratio of prepregnant body mass index (8MI), gestational weight gain (GWG), and gestational diabetes mellitus (GOM) for excessive fetal growth, which we define as large for gestational age (LGA). Methods: We included 16,297 women who delivered a live-born singleton baby at term. We fit logistic regressions to estimate the odds ratios of variables. including maternal age. parity. prepregnant BMI2``:23, GWG 2``:15 kg, and GOM, for LGA We classified GWG into four categories "10, 10-14.9. 15-19.9. and 2``:20 kg) and 8MI into four categories (underweight, normal, overweight, and obese). After adjusting for age and parity, we analyzed the odds ratios of prepregnant 8MI according to GWG between non~GOM and GOM women for LGA Results: The odds ratios of GWG ≥2``:15 kg and prepregnancy 8MI ≥23 for LGAwere 2.40 (95% confidence interval [CI1. 2.16-2.67) and 2.24 (95% CI, 1.99-2.51), respectively. The odd ratio of GOM was 1.37 (95% CI, 1.09-1.71). The risk of 80M women with normal/-overweight 8MI and GWG <15 kg for LGA was not significantly greater than those of the reference group. The odd ratios of GDM women with overweight/obese BMI and GWG 15 to 19.9 kg were 3.95 (95% CI, 1.26-12.38) and 9.70 (95% CI, 3.79-24.87), respectively. Conclusion: GWG 2``:15 kg might be a more important risk factor for LGA than either prepregnancy BMI 2:23 or GDM. Risk for LGA was highest in obese GOM women with GWG ≥2:15 kg.