한국인 담석중의 특성 및 변화에 대한 임상적 고찰 = Changing State and Present Features of Gallstone Disease in Korea

다국어 초록 (Multilingual Abstract)

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다국어 초록 (Multilingual Abstract)

Objectives: The incidence of gallstone disease seems to be increasing and the composition of stone has been changed in Korea. Therefore, a collective review of 4, 491 gallstone patients during the last twenty years from january 1973 to December 1992 were carried out at Hanyang university hospital, Seoul, Korea. Methods: The total prevalence of localization, physicochemical characteristics, blood type, associated diseases, and the composition of stones were evaluated retrospectively. The statistical analysis was evaluated by Student`s t-test. Results: 1) The prevalence among total hospitalized patient was 1.1% and showed increasing tendency annually. 2) The prevalence increased with age, reaching peak in 50 and the male/female ratio was 1:1.13 3) The prominent clinical manifestations included biliary pain (50.64%), fatty food intolerance (17.14%), jaundice (14.69%), and vomiting (11.73%). 4) The associated diseases were diabetes mellitus (29%), hypertension, chronic liver disease, pancreatitis, and Clonorchiasis. 5) The pigment stones were more prevalent than cholesterol stones (2.5:1), However, cholesterol stones seemed to be increasing gradually. Conclusion: These results indicate that most gallstones are pigment stones in Korea. However, the incidence of cholesterol stone seems to be increasing, and the overall incidence of gallstone disease is throught to be increasing annually.