Pulmonary histiocytosis X can be associated with disseminated histiocytosis X, but isolated case in the lung parenchyme is rare. We report a case of primary pulmonary histiocytosis X with recurrent pneumothoraces.
A 36-year-old man was referred beca...
Pulmonary histiocytosis X can be associated with disseminated histiocytosis X, but isolated case in the lung parenchyme is rare. We report a case of primary pulmonary histiocytosis X with recurrent pneumothoraces.
A 36-year-old man was referred because of recurrent pneumothorax. He had been suffered from dry cough and exertional dyspnea for 4 years. He was a heavy smoker. Plain chest X-ray and chest CT scan revealed thin-walled cysts of various sizes in both lungs. Open lung biopsy was performed. Light microscopic examination revealed proliferation arid infiltration of Langerhans'cells. Immunohistochemically, Langerhans`cells showed strong cytoplasmic staining with S-100 protein and electronmicroscopic examination showed Birbeck granules in Langerhans`cell.
He was treated with bleb resection and pleurodesis, but pneumothorax recurred 1 month later.