The Effect of Genetic-Based Personalized Nutrition Intervention on Weight Loss and Mindful Eating (MEQ) in Obese Subjects

다국어 초록 (Multilingual Abstract)

Personalized nutrition may be an effective strategy in the near future. We evaluated the effect of a 12-week genetic-based personalized randomized nutrition intervention on weight loss and health outcome in 62 obese adults. Physical measurements, body mass tests, blood profiles and MEQ etc before and after the study. nine obesity-related genes were assessed. Individualized nutrition counseling was performed once a week to the EG according to genetic risk factors for 12 weeks while CG received weekly SNS message. Body weight and body fat mass decreased significantly between weeks 0 and 12 in both the CG and the EG but the difference showed a greater weight loss effect in the EG than the CG (ΔCG-1.26±2.13 kg vs ΔEG-2.89±2.74 kg, p<0.05). As a result of genetic risk factors, among those with risk genes for gluttony, showed significant reduction in the total score of MEQ score (10±2.88 vs 6.14±2.19, P<0.05). CHO intake ratio was significantly decreased in the EG (53.8±1.98% to 44.3±2.16% p<0.05). In conclusion, we confirmed that genetic-based nutritional intervention can be served as an efficient tool.