γ-Linolenic Acid Methyl Ester from Rhizopus oryzae KSD-815 Isolated from Nuruk Induces Apoptosis in Prostate Cancer LNCaP Cells

참고문헌 (Reference)

1 Colquhoun A, "γ-Linolenic acid and eicosapentaenoic acid induce modifications in mitochondrial metabolism, reactive oxygen species generation, lipid peroxidation and apoptosis in Walker 256 rat carcinosarcoma cells" 1533 : 207-219, 2001

2 Bradham C, "p38 MAPK in development and cancer" 5 : 824-828, 2006

3 Sabatini DM, "mTOR and cancer: insights into a complex relationship" 6 : 729-734, 2006

4 Hay N, "Upstream and downstream of mTOR" 18 : 1926-1945, 2004

5 Cheng SWY, "Thr2446 is a novel mammalian target of rapamycin (mTOR) phosphorylation site regulated by nutrient status" 279 : 15719-15722, 2004

6 Shaw RJ, "The LKB1 tumor suppressor negatively regulates mTOR signaling" 6 : 91-99, 2004

7 Hardie DG, "The AMP-activated protein kinase pathwaynew players upstream and downstream" 117 : 5479-5487, 2004

8 Fingar DC, "Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression" 23 : 3151-3171, 2004

9 Li Y, "TSC2: filling the GAP in the mTOR signaling pathway" 29 : 32-38, 2004

10 Inoki K, "TSC2 mediates cellular energy response to control cell growth and survival" 115 : 577-590, 2003

11 Inoki K, "TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling" 4 : 648-657, 2002

12 Park MT, "Suppression of extracellular signal-related kinase and activation of p38 MAPK are two critical events leading to caspase-8-and mitochondria-mediated cell death in phytosphingosinetreated human cancer cells" 278 : 50624-50634, 2003

13 Galan A, "Stimulation of p38 mitogen-activated protein kinase is an early regulatory event for the cadmium-induced apoptosis in human promonocytic cells" 275 : 11418-11424, 2000

14 Shimada K, "Roles of p38-and c-jun NH2-terminal kinase-mediated pathways in 2-methoxyestradiol-induced p53 induction and apoptosis" 24 : 1067-1075, 2003

15 Dhillon AS, "MAP kinase signaling pathways in cancer" 26 : 3279-3290, 2007

16 Gunstone FD, "High-resolution 13C NMR spectra of longchain acids, methyl ester, glycerol esters, wax esters, nitriles, amides, alcohols and acetates" 66 : 189-193, 1993

17 Miyake JA, "Gammalinolenic acid inhibits both tumour cell cycle progression and angiogenesis in the orthotopic C 6 glioma model through changes in VEGF, Flt 1, ERK 1/2, MMP 2, cyclin D 1, pRb, p 53 and p 27 protein expression" 8 : 8-, 2009

18 Das UN, "From bench to the clinic: γ-linolenic acid therapy of human gliomas" 70 : 539-552, 2004

19 Thomas GV, "Antibody-based profiling of the phosphoinositide 3-kinase pathway in clinical prostate cancer" 10 : 8351-8356, 2004

20 Guertin DA, "An expanding role for mTOR in cancer" 11 : 353-361, 2005

21 Horowitz JC, "Activation of the pro-survival phosphatidylinositol 3-kinase/AKT pathway by transforming growth factor- 1 in mesenchymal cells is mediated by p38 MAPK-dependent induction of an autocrine growth factor" 279 : 1359-1367, 2004