재생 간조직의 비만세포 동태에 관한 연구 = Study on Dynamic Changes of Mast Cells in the Regenerating Rat Liver after Partial Hepatectomy

다국어 초록 (Multilingual Abstract)

This study was performed to investigate the dynamic changes of mast cells in the regenerating rat liver. The changes of number of mast cells and maturity of granules in mast cells were observed in toluidine blue, azure A, and alcian blue-safranin stained regenerating liver from 4 day after partial hepatectomy.
Results were as followings :
1. The total number of mast cells in the regenerating liver decreased to minimum at 16 day and then increased to the control level at 28 day.
2. A few of fine and lightly stained metachromatic granules were observed n the mast cell of 20 day, but these granules were more numerous and deeper stained in the mast cell of 28 day after partial hepatectomy.
3. At 28 day after partial hepatectomy, immature granule containing mast cells were increased but mature granule containing mast cells were decreased than those of the control.
From the above results, it was evident that the recovery of mast cell number and granule maturation in the regenerating liver was delayed than that of liver regeneration itself.
(Key words : Mast Cell, Liver Regeneration, Partial Hepatectomy)