Background: This study aims to investigate clinical features, angiographic fi ndings, and outcomes of young AMI patients. Methods: We analyzed major adverse cardiac events (MACE) in the Korea Acute Myocardial Infarction Registry from November 2005 to ...
Background: This study aims to investigate clinical features, angiographic fi ndings, and outcomes of young AMI patients. Methods: We analyzed major adverse cardiac events (MACE) in the Korea Acute Myocardial Infarction Registry from November 2005 to October 2010. Registered patients were divided into two groups, young age group (<45 years) and old age group (=65 years). Results: Young age group was composed of 1,248 patients (39.6±4.3 years) and old age group 9,759 patients (74.5±6.5 years). Male, smoking, family history and dyslipidemia were more frequent in young age group than those in old age group (96.6% vs. 57.5%, P<0.001; 86.9% vs. 45.7%, P<0.001; 15.5% vs. 4.8%, P<0.001; 13.4% vs. 9.5%, P<0.001). Young Korean adults with AMI had a shorter symptom-to-door (17.4±72.6 min vs. 24.2±77.7 min, P=0.002), but a longer door-to-balloon time (111.1±106.8 min vs. 101.8±92 min, P=0.043). The young age group had shown a favorable prognosis compared with old age group by Kaplan-Meier survival analysis (long-rank, P<0.001). However, there was no signifi cant difference in the adjusted MACE rate at one-year (HR 1.10, 95% CI 0.79-1.53, P=0.585), even after propensity-matched analysis (HR 0.80, 95% CI 0.52-1.23, P=0.307). Conclusions: Young Korean adults with AMI have similar clinical outcomes with old age patients, and therefore they should be treated aggressively like elderly patients.