갑상선유두상암에서 종양의 크기에 대한 수술 전 초음파검사소견과 수술 후 병리조직검사소견의 비교 = Comparison of Tumor Size in Papillary Thyroid Carcinoma: Between Preoperative Ultrasonographic and Postoperative Histopathologic Finding

다국어 초록 (Multilingual Abstract)

Background and Objectives: Size of thyroid tumor is one of important parameters in making decision for the surgical extent of thyroid resection and necessity of lymph node dissection in papillary thyroid carcinoma (PTC). Although tumor size by pathologic finding is important to evaluate the prognosis of patient with PTC, the decision of surgical extent depend on the preoperative ultrasonographic tumor size. The purpose of this study is to compare primary tumor size between preoperative ultrasonographic and pathologic results in PTC. Materials and Methods: From March 2008 to February 2009, 105 patients (22 males, 83 females) with PTC who were undergone ultrasonographic examination within 3 months before operation were reviewed retrospectively. We measured the longest diameter of tumor in both ultrasonographic findings and pathogic results and were compared with size according to tumor nature (solid vs mixed types) in both examination. Data was analyzed by linear regression analysis. Results: Mean preoperative ultrasonographic tumor size were greater than pathologic size. Decreasing rate of tumor size are 15.7% in all cases and 7.7% in the solid type. The tumor size by preoperative ultrasonosgraphy are strong correlation with size of pathologic results in all cases (n=105, γ²= 0.602, p＜0.05) and solid type (n=97, γ²=0.706, p＜0.05). But there is no significant correlation with size measured by ultrasonographic and pathologic findings in mixed type (n=8, γ²=208, p＞0.05). Conclusion: There are some size discrepancy between preoperative ultrasonographic findings and pathologic results, especially mixed type. The decision of surgical extent based on preoperative ultrasonographic finding would be considered its size discrepancy.