자연과학편 : 트레드밀 훈련방법이 척수손상 쥐의 운동기능 및 감각기능에 미치는 영향 = The effects of treadmill exercise method on motor and sensory recovery after spinal cord hemisection in rats

다국어 초록 (Multilingual Abstract)

Spinal cord injury (SCI) is often associated with variable loss of motor and chronic central pain syndromes. The present study examined the training effects of treadmill on motor and sensory recoveries in spinal hemisected rats. Under enflurane anesthesia, rats were subjected to spinal hemisection at T13. and then divided to three groups depending on exercise loads ; control, x 1 excercise and x 2 excercise in a day. Exercise began 1 day post surgery, lasted 25 min per day, 7 days a week for 3 weeks. Motor function as evaluating by BBB and CBS score showed predominant increase in exercise groups from early phase, load dependently, when it compared controls. There were significant differences among the three group. But treadmill exercise did not ameliorated mechanical and cold allodynia as measuring withdrawal frequency to von Frey hair and acetone application. These results suggested that treadmill exercise is effective increase the speed of motor function recovery and normalization of increased reflexes following SCI, but not sensory recovery.

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