임신중 혈청 C-반응성 단백의 정량분석에 관한 연구 = A Study of Quantitative Analysis of Serum C-Reactive Protein in Normal Pregnancy

다국어 초록 (Multilingual Abstract)

The objective of this study is to establish the normal level of serum C-reactive protein in Korean women with uncomplicated pregnancy. Serum C-reactive protein levels were determined by means of the turbidimetric immunoassay technique in 298 pregnant women at various gestational ages who visited the department of obstetrics and gynecology in Dae Han General Hospital during the period from September, 1988 to August, 1990. The range of gestational ages varied from 42 days(6 weeks) to 302 days (43+1 weeks). Followings are the results summarized. 1. The mean level of serum C-reactive protein in pregnant women was 0.48±0.45 mg/dl which was within normal limits. 2. There was statistically significant positive relation between gestational ages and serum C-reactive protein levels(r=0.194, P<0.01). 3. The mean levels of serum C-reactive protein were 0.35 mg/dl in the first trimester, 0.47 mg/dl in the second trimester, 0.57 mg/dl in the third trimester, and 0.48 mg/dl in the period of post-expected date of confinement. 4. The upper limit of C-reactive protein level defined as the ninty-fifth percentile was 1.38 mg/dl and the cases higher than 1.38 mg/dl were in 16 of 298 pregnant women.