Abstract Background: Hemostasis of upper gastrointestinal bleeding had been tried by various method. Method : Two-hundred-and-eight patients with upper gastrointestinal hemorrhage were treated by endoscopic local injection of hypertonic saline-epinep...
Abstract Background: Hemostasis of upper gastrointestinal bleeding had been tried by various method. Method : Two-hundred-and-eight patients with upper gastrointestinal hemorrhage were treated by endoscopic local injection of hypertonic saline-epinephrine (HSE) solution at our hospital during the 2-year period from February 1989 to January 1991. Result : The 208 cases included 115 gastric ulcers, 36 duodenal ulcers, 28 stomach cancers, 14 Mallory-weiss syndromes, 13 marginal ulers, and other diagnosis. A total of 45 cases (21.6%) had serious systemic diseases such as decompensatory liver cirrhosis, postoperative bleeding, malignant tumors of other organ, cerebrovascular disease and renal failure. In cases without serious systemic disease, permanent and temporary hemostasis were demonstrated in 98.8% and 1.2% respectively. In cases with serious systemic disease, permanent and temporary hemostsis were demonstrated in 68.9% and 17.8% respectively. An apparent hemostatic effect was not evident in 13.3%. Conclusion : Local injection of HSE solution can be repeated in large does and applied for various types of hemorrhage, producing excellent hemostasis.