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      KCI등재 SCOPUS

      생약의 조골 세포 증식과 분화 검색 = Activity of Medicinal Plants on Proliferation and Differentiation of Osteoblasts

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      https://www.riss.kr/link?id=A103820952

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      다국어 초록 (Multilingual Abstract)

      Osteoblasts play an important role in bone metabolism by bone formation. Natural medicines having a stimulatory
      activity on osteoblast proliferation and differentiation can improve bone diseases such as osteoporosis. The methanol extracts
      of 159 herbal medicines were screened for the stimulatory activity on osteoblast proliferation by MTT assay and differentiation
      in the presence of ascorbic acid and β-glycerophosphate. Among the tested extracts, Alpiniae Semen, Amomi Semen, Anemarrhenae
      Rhizoma, Bambusae Folium, Cannabis Semen, Dalbergiae odoriferae Lignum, and Luffae Fructus Retinervus
      showed relatively strong stimulatory activity on osteoblast proliferation, whereas Amomi Semen showed strong stimulatory
      activity on osteoblast differentiation.
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      Osteoblasts play an important role in bone metabolism by bone formation. Natural medicines having a stimulatory activity on osteoblast proliferation and differentiation can improve bone diseases such as osteoporosis. The methanol extracts of 159 herba...

      Osteoblasts play an important role in bone metabolism by bone formation. Natural medicines having a stimulatory
      activity on osteoblast proliferation and differentiation can improve bone diseases such as osteoporosis. The methanol extracts
      of 159 herbal medicines were screened for the stimulatory activity on osteoblast proliferation by MTT assay and differentiation
      in the presence of ascorbic acid and β-glycerophosphate. Among the tested extracts, Alpiniae Semen, Amomi Semen, Anemarrhenae
      Rhizoma, Bambusae Folium, Cannabis Semen, Dalbergiae odoriferae Lignum, and Luffae Fructus Retinervus
      showed relatively strong stimulatory activity on osteoblast proliferation, whereas Amomi Semen showed strong stimulatory
      activity on osteoblast differentiation.

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      참고문헌 (Reference)

      1 Jeong, J. C., "Stimulative effects ofDrynariae Rhizoma extracts on the proliferation and differentiationof osteoblastic MC3T3-E1 cells" 96 : 489-495, 2005

      2 Lee, J. W., "Ribavirin enhances osteoclast formationthrough osteoblasts via up-regulation of TRANCE/RANKL" 296 : 17-24, 2007

      3 Stein, G. S., "Relationshipof cell growth to the regulation of tissue-specific gene expressionduring osteoblast differentiation" 4 : 3111-3123, 1990

      4 Komori, T., "Regulation of osteoblast differentiation bytranscription factors" 99 : 1233-1239, 2006

      5 Lee, J. H., "Protective effect of Amomi semen extract on alloxaninducedpancreatic beta-cell damage" 22 : 86-90, 2008

      6 Lorenzo, J., "Osteoimmunology:interactions of the bone and immune system" 29 : 403-440, 2008

      7 Ducy, P., "Osf2/Cbfa1: a transcriptional activator of osteoblastdifferentiation" 89 : 747-754, 1997

      8 Fukui, H., "Novel functions ofherbal medicines in dendritic cells: role of Amomi Semen intumor immunity" 51 : 1121-1133, 2007

      9 Roodman, G. D., "Mechanisms of bone metastasis" 650 : 1655-1664, 2004

      10 Kikuyama, A., "Hydrogen peroxide inducesapoptosis of osteocytes: involvement of calcium ion andcaspase activity" 71 : 243-248, 2002

      1 Jeong, J. C., "Stimulative effects ofDrynariae Rhizoma extracts on the proliferation and differentiationof osteoblastic MC3T3-E1 cells" 96 : 489-495, 2005

      2 Lee, J. W., "Ribavirin enhances osteoclast formationthrough osteoblasts via up-regulation of TRANCE/RANKL" 296 : 17-24, 2007

      3 Stein, G. S., "Relationshipof cell growth to the regulation of tissue-specific gene expressionduring osteoblast differentiation" 4 : 3111-3123, 1990

      4 Komori, T., "Regulation of osteoblast differentiation bytranscription factors" 99 : 1233-1239, 2006

      5 Lee, J. H., "Protective effect of Amomi semen extract on alloxaninducedpancreatic beta-cell damage" 22 : 86-90, 2008

      6 Lorenzo, J., "Osteoimmunology:interactions of the bone and immune system" 29 : 403-440, 2008

      7 Ducy, P., "Osf2/Cbfa1: a transcriptional activator of osteoblastdifferentiation" 89 : 747-754, 1997

      8 Fukui, H., "Novel functions ofherbal medicines in dendritic cells: role of Amomi Semen intumor immunity" 51 : 1121-1133, 2007

      9 Roodman, G. D., "Mechanisms of bone metastasis" 650 : 1655-1664, 2004

      10 Kikuyama, A., "Hydrogen peroxide inducesapoptosis of osteocytes: involvement of calcium ion andcaspase activity" 71 : 243-248, 2002

      11 Yasui, T., "Hormone replacement therapy in postmenopausal women" 50 : 136-145, 2003

      12 Linares, G. R., "Glutaredoxin 5 regulates osteoblast apoptosisby protecting against oxidative stress" 44 : 795-804, 2009

      13 Pan, W., "Genistein stimulates the osteoblastic differentiationvia NO/cGMP in bone marrow culture" 94 : 307-316, 2005

      14 Kim, K. W., "Effect of safflower seeds supplementation on stimulationof the proliferation, differentiation and mineralizationof osteoblastic MC3T3-E1 cells" 115 : 42-49, 2008

      15 Yang, Q., "Effect of Angelica sinensis on the proliferation ofhuman bone cells" 324 : 89-97, 2002

      16 Hyun Mo Yang, "Cuscuta chinensis Extract Promotes Osteoblast Differentiation and Mineralization in Human Osteoblast-Like MG-63 Cells" 한국식품영양과학회 12 (12): 85-92, 2009

      17 Sasaki-Iwaoka, H., "A trans-acting enhancermodulates estrogen-mediated transcription of reporter genesin osteoblasts" 14 : 248-255, 1999

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      공동연구자 (7)

      유사연구자 (20) 활용도상위20명

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      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2023 평가예정 해외DB학술지평가 신청대상 (해외등재 학술지 평가)
      2020-01-01 평가 등재학술지 유지 (해외등재 학술지 평가) KCI등재
      2010-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2008-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2005-01-01 평가 등재학술지 선정 (등재후보2차) KCI등재
      2004-01-01 평가 등재후보 1차 PASS (등재후보1차) KCI등재후보
      2003-01-01 평가 등재후보학술지 유지 (등재후보1차) KCI등재후보
      2001-07-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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      학술지 인용정보

      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.42 0.42 0.39
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.42 0.41 0.803 0.05
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