A 21-year-old male was presented with sudden headache, fever, petechiae and neck stiffeness. The diagnosis of meningococcal meningitis was confirmed by examination of cerebrospinal fluid. The clinical symptoms of the illness were improved after treatm...
A 21-year-old male was presented with sudden headache, fever, petechiae and neck stiffeness. The diagnosis of meningococcal meningitis was confirmed by examination of cerebrospinal fluid. The clinical symptoms of the illness were improved after treatment of antibiotics. However the paient developed generalized edema, oliguria, azoternia, and heavy proteinuria in the recovery phas of illness. Low serum C3 level was also noted. A kidney biopsy was perfromed and showed the features of postinfectious glomerulonephritis and typical subepithelial humps on electron-microscopic examination. His sysmptoms and laboratory findings were improved, and C3 level re turned to normal range after conservative treatment. We suggest that a complement deficiency should be reled out in patients of glomerulonephritis developed during the recovery phase of meningococcal men ingitis. C3 nephritic factor detection and renal biopsy should be carefully considered in these patients. (Korean J Nephrol 2003;23(3):321-325