정상 초기임신의 혈중 β-hCG와 질식 초음파소견에 관한 연구 = The Study on Transvaginal Ultrasonography and Serum β-hCG in Normal Early Pregnancy

다국어 초록 (Multilingual Abstract)

Up to date, the transvaginal ultrasonography was used widespread through the world. Then the transvaginal ultrasonography and β-hCG were used to the early diagnosis of pregnancy and to the confirm of intrauterine pregnancy. Thereafter the aging of the embryo which normal development and well being can be suspected through the follow-up of gestational sac(G-sac) size, Crown-rump length(CRL) and serum β-hCG. Furthermore, we could predictate of pregnancy outcome through the finding time of fetal heart beat and CRL to G-sac ratio at ultrasonography. We conducted to estimate and follow-up the G-sac size and the CRL by transvaginal ultrasonography and serum β-hCG of the 119 early pregnant women who had visited to the our infertility clinic in period of April 1991 though May 1992, and had pregnancy throughout the ovulation induction. And we had results as below. 1. Linear relationships were found between the mean G-sac diameter and gestational age in early pregnancy. The G-sac diameter was 9.9mm±3.6 at 5th weeks and 49.6mm± 15.6 at 12th gestational weeks (r=0.640). 2. Linear relationships were found between the mean CRL growth and gestational age too, in early pregnancy. The CRL was 5.1mm±1.7 at 6th weeks and 47.2mm±10.5 at 12th gestational weeks (r=0.875). 3. The fetal heart beat could detect from 5th weeks (60.5%) to 7th weeks (100%) by transvaginal ultrasonography. At that time, over 10000mIU/ml of serum β-hCG level was 86 (72.3%) of 119 patients, and over 20000mIU/ml was checked by 100% of patients. 4. The serum level of β-hCG rise rapidly in an exponential manner from 47.1mIU/ml± 34 at 4th weeks to 84994.9mIU/ml±656 at 8th weeks and begin to plateau to 112150.0 mIU/ml±118844 at 12 weeks. 5. There is good indicator of pregnancy outcome that the ratio of G-sac to CRL is decreased which accompany to progression of pregnancy and embryo wellbeing.