This study was designed to observe the antitum effects of hot water soluble polysaccharides extract (PS) from the mushroom, Lentinus edodes and vitamin A against V653 cancer cells in vitro. The chemical components of PS fractions were analyzed and sur...
This study was designed to observe the antitum effects of hot water soluble polysaccharides extract (PS) from the mushroom, Lentinus edodes and vitamin A against V653 cancer cells in vitro. The chemical components of PS fractions were analyzed and survival time and cell number of V653 which were treated with extract fractions(Fr. A, Fr. B and Fr. C)were also measured. The results obtained were summarized as follows; The extract of fraction B was shown the highest antitumor activity against V653 implanted in ICR mice. The inhibitory effects of the hot water extracts from mushroom against cancer cell growth of V653 were stronger than the control group. And the survival time of ICR mice was shown 190 % between the control group and the experimental groups.