정상 체중 성인에서 체지방률과 심혈관계 위험인자의 관련성 = Association Between Percent Body Fat and Cardiovascular Risk Factors in Normal Weight Korean Adults

다국어 초록 (Multilingual Abstract)

Background: Obesity is associated with metabolic syndrome and cardiovascular risk factors. We examined metabolic syndrome and cardiovascular risk factors by percent body fat difference in adult with normal weight adults.
Methods: We analysed 353 subjects whose body mass index (BMI) were between 18.5 and 23 kg/m2. They were examined in a health promotion center of a general hospital from Jan. to Dec. 2009. Age, gender, height,weight, BMI, waist circumference (WC), systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting blood sugar (FBS), hemoglobin A1C, lipid profiles, fat free mass, lean body mass, body fat mass, percent body fat (%BF) were checked. Subjects were divided into two groups according to their %BF by 25% in men, 30% in women and analysed about metabolic syndrome and cardiovascular risk factors.
Results: The average age was 47.30±10.83 years old, and BMI was 21.75±1.32 kg/m2, %BF was 22.92±5.53%in men, 26.67±6.32% in women. High %BF group showed increased BMI, WC, SBP, DBP, serum FBS, total cholesterol, triglyceride, low-density lipoprotein cholesterol and body fat mass decreased high-density lipoprotein cholesterol, fat free mass and lean body mass. High %BF group showed increased frequency of metabolic syndrome components, hypertension, and dyslipidemia. Diabetes was increased in high %BF group of women. The result of binary logistic regression analysis with age adjusted, metabolic syndrome, hypertension and hyperlipidemia was related with %BF in men, metabolic syndrome, diabetes, hypertension, hyperlipidemia was related with %BF in women.
Conclusions: High %BF was associated with metabolic syndrome and cardiovascular risk factors like hypertension,dyslipidemia in both men and women with normal weight. But, high %BF was associated with diabetes in only women in this study.

국문 초록 (Abstract)

연구배경: 비만은 대사증후군 및 심혈관계 질환과 밀접한 관련이 있는 것으로 알려져 있지만, 정상 체중 성인에서도 대사증후군이나 심혈관계 위험인자를 가지고 있는사람들이 있다. 따라서 정상 체중 성인에서 체지방률에 따른 대사증후군과 심혈관계 질환의 위험도를 알아보고자하였다.
방법: 2009년 1월부터 12월까지 일개 대학병원의 건강증진센터에 내원한 수진자 중 체질량지수가 18.5 kg/m2 이상23 kg/m2 미만인 성인 353명(남성 176명, 여성 177명)을 대상으로 연령, 성별, 신체계측, 혈압, 공복혈당, 당화혈색소,혈청지질대사치, 과거병력 설문조사, 체성분(생체전기저항분석법) 분석을 시행하였다. 남성의 경우 체지방률 25%,여성의 경우 체지방률 30%를 기준으로 낮은 군과 높은 군으로 나누어 각 군의 특성과 대사증후군 인자와 심혈관계위험인자를 분석하였다.
결과: 남녀 모두 체지방률이 높은 군에서 체질량지수,허리둘레, 수축기혈압, 이완기혈압, 공복혈당, 총콜레스테롤, 중성지방, 저밀도콜레스테롤, 체지방량이 높았고, 고밀도 콜레스테롤, 제지방량, 근육량은 낮았다. 당화혈색소는남성의 경우에만 통계적으로 유의하였다. 남녀 모두 체지방률이 높은 군에서 대사증후군과 그 구성인자의 빈도가높았으며, 심혈관계 위험인자 중 고혈압, 고지혈증의 빈도가 높았다. 당뇨병은 여성에서만 통계적으로 유의하게 높은 빈도를 보였다. 연령을 보정한 교차비 분석 결과 남녀모두에서 체지방률이 높은 군에서 대사증후군, 고혈압, 고지혈증이 높은 교차비를 보였다. 당뇨병의 경우, 여성에서만 높은 교차비를 보였다.
결론: 정상 체중 성인에서 체지방률이 높으면 남녀 모두대사증후군 및 고혈압, 고지혈증과 같은 심혈관계 위험도가 증가하였고, 여성의 경우에는 당뇨병의 위험도도 증가하였다.

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