EMLA 크림이 ampicillin sodium 항생제 피내반응검사에 미치는 효과

다국어 초록 (Multilingual Abstract)

Purpose: The purpose of this study was to identify the effects of EMLA cream (eutectic mixture of local anesthetics, lidocaine and prilocaine) on pain during ampicillin sodium intradermal (ID) skin test, and also to assess skin reaction after the skin test. Methods: Forty-three nurse-volunteers had skin tests with 0.01ml-0.05ml ampicillin sodium antibiotics. Skin tests were done on each forearm to compare the pain level of the skin test site after application of EMLA cream with the pain level when no EMLA cream was applied. EMLA cream was applied at the ID skin test site with an occlusive dressing for one hour. Pain was evaluated using a visual analogue scale and pain sensation using the short form McGill Pain Questionnaire. The transverse diameter of the wheal and redness was read right after and at 15 minutes after the skin test. The results were compared using independent t-tests. Results: Pain score and sensation with EMLA cream treatment were significantly lower than when EMLA cream was not applied. There was no difference in skin reactions; reading of the skin test was not affected by EMLA cream. Conclusions: EMLA cream was found to be an effective local anesthetic to relieve the pain of clients having ampicillin sodium antibiotics ID skin tests.

참고문헌 (Reference)

1 정용선, "피부국소마취제가 아동의 정맥천자시 통증 경감과 불안 감소에 미치는 효과" 아동간호학회 12 (12): 253-259, 2006

2 최자윤, "당뇨환자와 일반인의 혈당검사 방법 별 지각된 통증정도에 대한 비교" 한국간호과학회 33 (33): 928-935, 2003

3 Britt, R. B, "Using EMLA cream before venipuncture" 35 (35): 17-, 2005

4 Dubus, J. C, "Use of lidocaine-prilocaine patch for the mantoux test: Influence on pain and reading" 327 : 78-80, 2006

5 Nagengast, S. L, "The use of EMLA cream to reduce and/or eliminate procedural pain in children" 8 : 406-407, 1993

6 Rogers, T. L, "The use of EMLA cream to decrease venipuncture pain in children" 19 : 33-39, 2004

7 Melzack, R, "The short-form Mcgill pain Questionnaire" 30 : 191-197, 1987

8 Jung, Y. M, "The effects of cold therapy on pain in patients with chest tube insertion" Yonsei University, Seoul.

9 Pae, H. C, "The effects of EMLA on pain associated with retrobulbar injection" 41 : 119-125, 2000

10 Oh, H. S, "The effect of topical EMLA cream on venipuncture related pain, anxiety and physiologic variables of preoperative autologous blood deposit patients" Kyung-Hee University, Seoul. 2009

11 Neal, M. J, "Medical pharmacology at a glance series" London: Blalckwell Science 2002

12 Park, J. S, "Literature review of nonpharmacologic pain management and pain management program" 4 : 33-53, 2000

13 "Institut fϋr Experimentelle Psychologie, Heinrich Heine Universtἃt Dϋsseldorf"

14 "Health insurance review & assessment service data"

15 Song, G. A, "Fundamentals of nursing interventions & skills" Seoul: Soomoonsa 2008

16 Greenberger, P. A, "Fatal anaphylaxis: postmortem findings and associated comorbid diseases" 98 : 252-257, 2007

17 Iancovici-Kidon, M, "Effect of EMLA cream on pain reduction and wheal response to diagnostic allergy skin testing" 4 : 898-898, 2002

18 Kaya, G, "EMLA cream application for epidural puncture" 32 : 54-58, 2004

19 "Druginfo. kr data"

20 Choi, E. S, "An analysis of the conceptof pain" 7 : 284-292, 2001

21 Taddio, A, "A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates"

22 Kaur, G, "A randomized trial of eutectic mixture of local anesthetics during lumbar puncture in newborns" 157 : 1065-1670, 2003

23 Shin, M. O, "A comparison of pain reducing effects of topical EMLA cream and subcutaneous lidocaine in hemodialysis patients" 2 : 37-43, 1995