식도정맥류 경화요법과 위점막 변화 = A Study of Endoscopic Injection Sclerotherapy and Gastric Mucosal Changes

다국어 초록 (Multilingual Abstract)

Endoscopic features of gastric mucosa in patients with various kinds of liver diseae have caught the attention of investigators in recent past. Gastric mucosal changes are frequently observed in cirrhotic patients and have been related with portal hypertension. Although controversial results have recently been reported, much evidence exists suggesting that the underlying alteration is a mucosal vasculopathy characterized by vascular ectasis, whereas mucosal inflammation have been reported to be infrequent. In evaluating gastric mucosal changes and assuming gastric mucosal blood flow as its cause, the author observed the fiderscopic mucosal findings in 71-liver cirrhosis patients with portal hypertension. The aim of study was to investigate the relationship between variceal form and incidence of gastric mucosal changes, mucosal findings before and after sclerotherapy, gastric mucosal changes according to degree of mucosal destructions of esophageal varices, duration of disappearance of gastric mucosal changes, There was no singificant relationship between the presence of gastropathy and the degree of esophageal varices. Before sclerotherapy, incidence of gastropathy was mosaic pattern 46.4%, hyperemia 15.5%. Sclerotherapy of esophageal varices was significantly increased the incidence and severity of gastropathy. The more destructions of esophageal varices by sclerotherapy were severe, the more time that mucosal changes of post0sclerot herpy returned to those of pre-sclerotherpay were significantly delayed. In conclusion, these observation suggests that the endoscopic changes of the gastric mucosa in patienst with portal hypertension were influenced by the gastric mucosal blood flow.