척추 수술후 C-반응 단백 및 적혈구 침강 속도의 정량분석 = Quantitation of C-reactive Protein Levels and Erythrocyte Sedimentation Rate after Spinal Surgery

다국어 초록 (Multilingual Abstract)

Objectives : In order to standardize the CRP, ESR and WBC count after three types of spinal surgery and get clinical usefulness from these laboratory datas after spinal surgery and clinical usefulness of laboratory datas.
Material and Methods : Three groups of patients(microdisectomy, anterior and posterior fusion) were chosen for the study. CRP, ESR and WBC levels were prospectively determined before surgery and at days 1-5, 10, 14, 21 and 42 after surgery
Results : In all patients, preoperative normal CRP level(<10㎎/L) increased, reaching peak levels on the second day after anterior fusion(84.6㎎/L), and at the third day after microdiscectomy(54.5㎎/L) and posterolateral intercorporal fu sion(152.2㎎/L), with normalization in 5-10 days. Preoperative normal ESR `level increased to peak level on the forth day after microdiscectomy(33.0㎜/hr), and increased double peak levels after anterior(postoperative days 2&5) and posterolateral intercorporal fusion(postoperative days 3&5). ESR followed by a slow and irregular decrease, and at 42 days after surgery often remained elevated. WBC increased to variable peak level within normal limit in all patients.
Conclusions : The rapid decline in CRP will probably be interrupted by a second rise or persisting elevation if infection occurs. CRP is presumably a better test than ESR for early detection of postoperative infection.